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39909

Assessment of Serum Level of 25-Hydroxy Vitamin D in Patients with Acne Vulgaris

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Last updated: 03 Jan 2025

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Abstract

Background: acne vulgaris is a common chronic inflammatory disease of the pilosebaceous unit, characterized by the formation of non-inflammatory comedones and inflammatory papules, pustules, nodules and cysts. Objective: the aim of this study was to evaluate serum levels of vitamin D in a group of Egyptian patients with acne vulgaris in comparison to controls, in order to shed more light on its possible role in the pathogenesis and detect any relation between vitamin D and acne severity. Patients and Methods: the study recruited 90 subjects, 60 acne vulgaris patients and 30 age and sex matched healthy controls. All patients were subjected to detailed history taking and examination to detect extent and severity of acne vulgaris. Blood samples were taken from all participants to assess serum 25 OH D level. Results: revealed lower serum vitamin D levels in acne patients in comparison to controls, with statistically significant p value (0.009). Serum 25 OH D level showed no significant difference in females than in males in both patients (p = 0.726) and controls in comparison to patients (p = 0.794). There was no significant difference in level of 25 OH D between participants reporting adequate sun exposure and those reporting inadequate sun exposure in patients (p = 0.804) but it was statistically significant p value in controls in comparison to patients (p < 0.001). Conclusion: the present study revealed lower, statistically significant, serum vitamin D levels in acne patients, suggesting a possible role for vitamin D supplementation in acne treatment.

DOI

10.21608/ejhm.2019.39909

Keywords

25-Hydroxy Vitamin D, Acne vulgaris

Authors

First Name

Abd El-Raouf Mohamed

Last Name

Elmohsen

MiddleName

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Affiliation

Department of Dermatology, Venerology and Andrology, Faculty of Medicine – Al-Azhar University

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Orcid

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First Name

Hassan Mamdouh

Last Name

Abd El-Aziz

MiddleName

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Affiliation

Department of Dermatology, Venerology and Andrology, Faculty of Medicine – Al-Azhar University

Email

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City

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Orcid

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First Name

Nagah Mohamed

Last Name

Abo Mohamed

MiddleName

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Affiliation

Department of Clinical Pathology, Faculty of Medicine – Al-Azhar University

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City

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Orcid

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First Name

Amr Farag Ibrahim

Last Name

Dabash

MiddleName

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Affiliation

Department of Dermatology, Venerology and Andrology, Faculty of Medicine – Al-Azhar University

Email

amrafandy8@gmail.com

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Orcid

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Volume

76

Article Issue

3

Related Issue

6364

Issue Date

2019-07-01

Receive Date

2019-07-08

Publish Date

2019-07-01

Page Start

3,678

Page End

3,683

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_39909.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=39909

Order

10

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Assessment of Serum Level of 25-Hydroxy Vitamin D in Patients with Acne Vulgaris

Details

Type

Article

Created At

22 Jan 2023