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29719

The Effects of Vitamin D Supplement on Prevention of Recurrence of Preeclampsia in Pregnant Women with a History of Preeclampsia

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Last updated: 03 Jan 2025

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Abstract

Background: Many studies hypothesized a strong relation between vitamin D level during pregnancy and the frequency of recurrent preeclampsia (PE). Objectives: The aim of the current study was to determine the effect of vitamin D supplement on reducing the probability of recurrent preeclampsia in pregnant women with history of preeclampsia. Patients and Methods: The study population included 50 women having a history of preeclampsia in previous pregnancies. They were referred to the obstetrical clinic in Diarb Negm Centeral Hospital in Diarb Negm City, for prenatal care. Women were classified into two groups, the first one (I) received 25-hydroxy vitamin D supplements and the other (II) received placebo. Results: Eight patients had pre-eclampsia in group II (34.8%) while in group I only 4 patients had preeclampsia (16%) (p=0.133). There were no significant statistical differences between the two groups according to pre-eclampsia incidence. The mean vitamin D level was 25.72 ± 7.69 and 28.33 ± 7.40 among patients without and with preeclampsia respectively. (p=0.309) there were no significant relation between the preeclampsia incidence and vitamin D level. Conclusion: vitamin D supplement may not have a role in prevention of preeclampsia recurrence.

DOI

10.21608/ejhm.2019.29719

Keywords

preeclampsia, Vitamin D, Eclampsia

Authors

First Name

Abd-Alsameea Hassan

Last Name

Khalifa

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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First Name

Mohamed Mohamed Ibrahim

Last Name

Farahat

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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Orcid

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First Name

Ahmed Fadel Abdel Hameed

Last Name

Mohamed

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

noor_dodo2007@hotmail.com

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Orcid

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Volume

75

Article Issue

1

Related Issue

5149

Issue Date

2019-04-01

Receive Date

2019-04-06

Publish Date

2019-04-01

Page Start

2,081

Page End

2,088

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_29719.html

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https://ejhm.journals.ekb.eg/service?article_code=29719

Order

26

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

The Effects of Vitamin D Supplement on Prevention of Recurrence of Preeclampsia in Pregnant Women with a History of Preeclampsia

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Article

Created At

22 Jan 2023