Background: Fractures of the proximal humerus are relatively common, accounting for about 5% to 9% of all fractions. Majority of undisplaced proximal humeral fractures can be treated with a sling immobilization and physical therapy. However, approximately 20% of displaced proximal humeral fractures require surgery. Objective: The aim of the current study was to assess the expected outcomes and complication rate of proximal humerus fractures treated with Proximal Humerus Internal Locking System (PHILOS) plating. Patients and Methods: This prospective study included a total of 15 patients with fracture of the proximal humerus attending at Department of Orthopedic Surgery, Al-Azhar University Hospitals. This study was conducted between January 2018 to October 2018. All cases were surgically managed by fracture fixation procedures (PHILOS). The follow up period of the cases is 6 months. Results: From analysis of the literature concerning the use of PHILOS plates, our results were satisfying in terms of functional recovery, with Constant Scores 73.67 that range between (48%–94%). Data from our survey show that most of patients were satisfied. We have noticed that limited functional recovery was usually caused by incorrect or delayed rehabilitation. The complication rate in our study (26.66%) is comparable to the literature, where the most recent studies report complication rates between 32 and 50%. Conclusion: More accurate length measurement and shorter screw selection should prevent primary screw perforation.