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Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery

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Last updated: 03 Jan 2025

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Abstract

Background: Hypotensive anesthesia represents a great challenge for the anesthetists. Although, there is great benefit from inducing hypotensive anesthesia, there is a great risk of major morbidity and mortality.
Aim of this work: Evaluation of the optimal dose of MgSo4 to create hypotension during functional endoscopic sinus surgery.
Materials and methods: This prospective, control, randomized, clinical study was conducted on 60 patient divided into three groups. Patients were recruited from the Department of Anesthesia and Intensive Care, AL- Azhar University Hospitals. Each group received different dose of MgSo4 5-10-15 mg/kg/h. Then, we took measures of Bp, Spo2, HR and cortisol. Our observations then were statically analyzed.
Results: There was more stability in hemodynamic parameter in group II and III. There was significant decrease in blood pressure in group III. In addition, there was a decrease in heart rate in group II and III but this decrease wasn't significant. Magnesium sulphate decreased release of stress hormone especially in group III.
Conclusion: Deliberated hypotension is very useful during surgery to decrease time and blood loss. Magnesium sulphate is one of the most useful techniques to induce hypotension during surgical operation. We suggest that using magnesium sulphate in 40 mg\kg as loading dose then continuous infusion at 15 mg\kg\h is the most effective and safest technique. Magnesium sulphate is very useful agent to abolish stress response.

DOI

10.21608/ejhm.2019.28676

Keywords

magnesium sulfate, Technique, Hypotensive Anesthesiam, Endoscopic sinus surgery

Authors

First Name

Hamed A.

Last Name

Sanad

MiddleName

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Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

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City

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Orcid

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First Name

Amgad Z.

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Ahmed A.

Last Name

Abd-elraouf

MiddleName

-

Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

zizoa3145@gmail.com

City

-

Orcid

-

Volume

74

Article Issue

8

Related Issue

5084

Issue Date

2019-01-01

Receive Date

2019-03-13

Publish Date

2019-01-01

Page Start

1,759

Page End

1,768

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 74_Issue 8_Pages 1759-1768.pdf

PDF . 280.1kB

Link

https://ejhm.journals.ekb.eg/article_28676.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=28676

Order

11

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery

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Article

Created At

22 Jan 2023