Background: High myopia is a common eye health problem due to its sight threatening complications. Using the newly introduced noninvasive devices, it's easier now to assess the morphological, anatomical and pathological changes accompanied with high myopia. Objectives: The aim of this study was to assess retinal vascular plexuses and choriocapillaris density and measuring the FAZ in the SCP & DCP with also assessment of central macular and subfoveal choroidal thickness in high myopia in adults using enhanced depth imaging optical coherence tomography angiography. Patients and Methods: This prospective observational study was carried out from June 2018 to November 2018 on 75 eyes of patients attending outpatient clinic of Ophthalmology department of Research Institute of Ophthalmology in Giza. Results: The best corrective visual acuity in the normal group was statistically significantly higher than the Myope group. The Macular thickness in the normal group was statistically significantly higher than the Myope group. The choroidal thickness in the normal group was statistically significantly higher than the Myope group. The FAZ DCP in the Myope group was statistically significantly higher than the normal group. Conclusion: The OCTA is certainly able to take over other invasive imaging techniques and new researches using this device might be able to study different pathologies affecting the posterior segment.