24360

The outcome of Antegrade Cerebral Perfusion during Deep Hypothermic Circulatory Arrest in Pediatric Arch Surgery

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Last updated: 03 Jan 2025

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Abstract

Background:  Techniques for the surgical correction of aortic aneurysms have steadily improved since the first described successful repair, Despite these improvements, postoperative neurological complications remain a major factor in determining an adverse outcome.Complex aortic arch reconstruction in neonates and children is performed typically under deep hypothermic circulatory arrest. Aim: The study aimed at examining the effect of clinical impact, particularly neurologic complications, of deep hypothermic circulatory arrest in pediatric arch surgery and to summarize the early outcomes. Patients and method: One-handed and fourteen underwent full-term babies were enrolled in the present study .The  maximum age was  20 weeks, arch surgery included  Norwood, arch reconstruction for hypoplastic arch and interrupted aortic arch. Healthy neurological status preoperative was included between January 2011 and October 2015. The medical records were reviewed for preoperative diagnosis of patients which included age at the time of operation, sex and diagnosis of the patients. Operative details including type of the operation, duration of cross-clamp and deep hypothermic circulatory arrest timing were documented.  The deep hypothermic circulatory arrest was conducted at 20 ℃. Postoperative outcomes, neurological complications including seizers, cerebral infarct, and duration of hospital stay were recorded. Results: The study noted that the incidence of postoperative complications such as seizure & bleeding was markedly 5.3%& 1.8% of the studied pediatric patients. Conclusion: The results concluded that the aortic arch reconstruction with Antegrade cerebral perfusion during the deep hypothermic circulatory arrest was accompanied by a lower risk of neurological complications. Recommendations: Long-term neurodevelopmental follow-up of these children is required to evaluate the late outcomes of Antegrade cerebral perfusion.

DOI

10.21608/ejhm.2019.24360

Keywords

Aortic Arch Surgery, Antegrade Cerebral Perfusion, Deep Hypothermic Circulatory Arrest, Neurological complications

Authors

First Name

Hyam Refaat

Last Name

Tantawi

MiddleName

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Affiliation

Pediatric department , Ain Shams University, Faculty of Medicine –Cairo University

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Orcid

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First Name

Mohamed

Last Name

Abdel Hafez

MiddleName

-

Affiliation

Cardiothoracic department, Faculty of Medicine –Cairo University

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Orcid

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Volume

74

Article Issue

4

Related Issue

4427

Issue Date

2019-01-01

Receive Date

2019-01-14

Publish Date

2019-01-01

Page Start

820

Page End

826

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_24360.html

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https://ejhm.journals.ekb.eg/service?article_code=24360

Order

15

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

The outcome of Antegrade Cerebral Perfusion during Deep Hypothermic Circulatory Arrest in Pediatric Arch Surgery

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Article

Created At

22 Jan 2023