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23800

Comparative study between corneal biomechanical parameters in the diabetic patients and normal individuals using ocular response analyzer (ORA)

Article

Last updated: 30 Jan 2023

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Abstract

Background: the cornea exhibits viscoelastic properties, which give it the quality of hysteresis. Corneal hysteresis is an important indicator of the biomechanical properties of the cornea. Objective: this study aimed to show the impact of diabetes on corneal biomechanics and to compare corneal biomechanics in diabetic to that in healthy non diabetic individuals using ocular response analyzer (ORA). Patients and Methods: we conducted our study on the diabetic patients and healthy non diabetic individuals to detect the relation between diabetes mellitus and the corneal biomechanics. Our study was performed on 120 eyes of 60 individuals as we categorized them into three groups. Group A involved 40 eyes from 20 controlled diabetic patients, group B involved 40 eyes from 20 non-controlled diabetic patients and 40 eyes from 20 healthy non diabetic individuals (Group C). Results: our study reported that diabetes mellitus led to an increase in corneal biomechanics as CH and CRF were elevated in patients with diabetes mellitus (Groups A & B). Conclusion: the corneal biomechanics in the diabetic groups were significantly higher compared to those of the control group, as the mean CH was 9.23 ± 0.98 mmHg in the controlled diabetic group (Group A), 10.11 ± 0.44 mmHg in the noncontrolled diabetic group (Group B) and is 8.03 ± 0.94 mmHg in the healthy non-diabetic individuals (Group C). The difference in CH between the three groups was statistically highly significant (P = 0.00). Meanwhile, the mean CRF was 9.26 ± 1.35 mmHg in the controlled diabetic group (Group A), 10.03 ± 0.99 mmHg in the non-controlled diabetic group (Group B) and 8.37 ± 0.56 mmHg in the healthy non-diabetic individuals (Group C). The difference in CRF between the three groups was statistically highly significant (P=0.00).

DOI

10.21608/ejhm.2019.23800

Keywords

cornea, ocular response analyzer, Corneal Hysteresis, corneal resistance factor, intra-ocular pressure, Diabetes mellitus, corneal compensated intra-ocular pressure, Goldman correlated intra-ocular pressure

Authors

First Name

Adel Abd El-Rahman

Last Name

Osman

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Al-Azhar University

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City

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Orcid

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First Name

Ehab Abd-Elsamea

Last Name

El-Sheikh

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Al-Azhar University

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Orcid

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First Name

Ayman Shawky Abd El-Haleim

Last Name

El-Sanhoury

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Al-Azhar University

Email

aymanshawkysanhoury@gmail.com

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Orcid

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Volume

74

Article Issue

3

Related Issue

4351

Issue Date

2019-01-01

Receive Date

2019-01-06

Publish Date

2019-01-01

Page Start

684

Page End

693

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_23800.html

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https://ejhm.journals.ekb.eg/service?article_code=23800

Order

28

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

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Article

Created At

22 Jan 2023