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21925

Study of the Effect of Repetitive Transcranial Magnetic Stimulation on a Sample of Children with Attention-Deficit/Hyperactivity Disorder

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Last updated: 24 Dec 2024

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Abstract

Background: attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neuropsychiatric disorder that affects children and young adults and cause significant functional impairment. Although there are effective medications and psychobehavioural therapies that help with management of ADHD, the medications can have significant side effects, which limit their use. There is need to explore other treatment options. transcranial magnetic stimulation (TMS) and repetitive transcranial magnetic stimulation (rTMS) are recent safe and non-invasive investigative and therapeutic tools. Aim of the work: to study the effect of repetitive transcranial magnetic stimulation on a sample of children with Attention-Deficit/Hyperactivity Disorder. Methods: the sample was consisted of (35) child; their ages were ranged from 6 to 12 years old after diagnosed clinically according to DSM-5 through a designed semi structured interview and through application of Conner's teacher-28 and parent-48 rating scalesas ADHD combined type. Females were (11) children with percentage 31.4%, while males were (24) children with percentage 68.6%. All patients on the sample were not receiving any medical or behavioral therapy for ADHD. Results: means scores of inattention, hyperactivity and impulsivity were reduced significantly in the post 5 days and 2 weeks follow up (P-values > 0.001(, started to rise again in its evaluation after 4 weeks but not reaching its values before rTMS sessions. the percentage of severe cases in each scale category was dramatically decreased immediately and 2 weeks after rTMS sessions and started to rise again in its evaluation after 4 weeks but to lower percent than before rTMS sessions (70%, 100% and 60% had severe inattention, hyperactivity and impulsivity respectively before rTMS, reduced to 0%, 0%, 10% immediately and 2 weeks after rTMS but increased to (20%, 40% and 40%) after 4 weeks. no patient experienced any significant adverse effects during the study, except 3 children reported mild headache that resolved spontaneously within an hour without medication. Conclusion: this study concluded that r TMS over left dorso-lateral prefrontal cortex may be safe and effective way of providing relatively lasting relief of ADHD symptoms especially in children with severe symptoms.

DOI

10.21608/ejhm.2018.21925

Keywords

ADHD – neurobiology – TMS – rTMS

Authors

First Name

Abdullah Ahmed Abdullah

Last Name

Mekky

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Affiliation

Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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First Name

Amgad Ahmed Moshref

Last Name

Gabr

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Affiliation

Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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First Name

Mohamed Ahmed Lotfy

Last Name

Kamal

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Affiliation

Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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First Name

Mohamed Mahmoud

Last Name

Hamouda

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Affiliation

Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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First Name

Ahmed Said Abd El Khalik

Last Name

Khalil

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Affiliation

Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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drahmedsaid8@gmail.com

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Volume

73

Article Issue

11

Related Issue

4124

Issue Date

2018-10-01

Receive Date

2018-12-13

Publish Date

2018-10-01

Page Start

8,084

Page End

8,090

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_21925.html

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https://ejhm.journals.ekb.eg/service?article_code=21925

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29

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Study of the Effect of Repetitive Transcranial Magnetic Stimulation on a Sample of Children with Attention-Deficit/Hyperactivity Disorder

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Article

Created At

22 Jan 2023