Background: post cesarean section pain is associated with a variety of unfavorable post-operative consequences; affect both mother and the newborn, especially the first 48 h after delivery. The pain can be improbable, disrupting mother/child bonding and also affects mental, chest, heart problems, and prolong the hospital stays. Aim of the Work: to compare the efficacy and safety of bilateral continuous transversus abdominis plane (TAP) block versus continuous wound infiltration for pain relief after surgery. Patients and Methods: this study was conducted on forty patients of American Society of Anesthesiologists (ASA) physical status I or II, scheduled for elective CS were enrolled in this controlled study. Information about the study was explained comprehensively both orally and in written form to the patients. All patients gave written informed consents prior to their inclusion in the study. Results: there was no difference between TAP block & CWI as regarding pain during rest but TAP block was more effective during movement than CWI, opioid consumption was much less in TAP group than in CWI group and the time of first analgesia request was earlier in CWI group than in TAP group. Conclusion: both TAP block & CWI provided post-operative analgesia but USG TAP block increased the time to first analgesic request, reduces the total pethidine consumption with hemodynamic stability and decreases the incidence of adverse effects in patient undergoing caesarian section compared to continuous wound infiltration.