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18936

Histological and Quantitative Study of the Effect of Eruca Sativa Seed Oil on The Testis of Albino Rat

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Last updated: 03 Jan 2025

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Abstract

Eruca Sativa (E.S) or Gargir seed oil is widely used in folk medicine. This study was conducted to investigate its possible effect on male rat fertility. Histological changes of the testis, level of testosterone hormone and sperm count were determined. The results revealed that administration of low dose of E.S. seed oil caused dilatation of the seminiferous tubules, proliferation of spermatogenic cells and increase of its mitotic activity. Increased number of sperms and epididymis weight, elevated level of testosterone hormone and hyperplasia of interstitial Leydig cells have also been noticed. DNA analysis revealed an increase of the percentage of haploid and decrease of diploid and tetraploid cells. Administration of E.S. seed oil at higher dose showed. decreased diameter of the seminiferous tubules, reduced spermatogenic activity and number of sperms . Also testosterone hormone level decreased and the interstitial cells appeared few. DNA analysis showed a reduction of the percentage of the haploid and increase of the percentage of diploid and tetraploid cells.

DOI

10.21608/ejhm.2001.18936

Authors

First Name

Mona A. R.

Last Name

Salem

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Affiliation

Histology Dep., Faculty of Medicine And Zoology Dep., Al-Azhar University (Girls)

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First Name

Nehal A.

Last Name

Moustafa

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Affiliation

Faculty of Science, Al-Azhar University (Girls)

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Volume

2

Article Issue

1

Related Issue

3895

Issue Date

2001-01-01

Receive Date

2018-11-13

Publish Date

2001-01-01

Page Start

148

Page End

162

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 2_Issue 1_Pages 148-162.pdf

PDF . 728.1kB

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https://ejhm.journals.ekb.eg/article_18936.html

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https://ejhm.journals.ekb.eg/service?article_code=18936

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Histological and Quantitative Study of the Effect of Eruca Sativa Seed Oil on The Testis of Albino Rat

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Article

Created At

22 Jan 2023