Background: digital subtraction angiography (DSA) is important diagnostic tool for evaluation of cerebral vasculature and provides essential information regarding hemodynamic status and collateral circulation in patients with stroke and vascular malformations, so it is ideal imaging method of choice for diagnosis of cerebrovascular diseases. Aim of the Work: to register all cases undergoing diagnostic cerebral angiography in Al-Hussein University hospital, neuro-intervention unit performed by a neuro-interventional team and evaluate the results, and outcome of this procedure. Materials and Methods: the present study is single-center study included all patients subjected to diagnostic cerebral angiography during period from 2006 to 2018. The study protocol was approved by the local Ethics Committee in Al-Azhar University. The patients had been recruited from Al-Hussein and Sayed Galal Hospital outpatient's clinics, internal departments and stroke units, which indicated for diagnostic cerebral angiography. Results: in the present study the mean age of patients with arterial stenosis was (55.47 ±8.80), 1049(51%) of them were males, 1009(49%) were females. In our study, mild stenosis was present in 254 (12.3%), moderate stenosis in 525 (25.5%), severe stenosis in 567 (27.6 %), subtotal occlusion in 315 (15.3%) and total occlusion in 397 (19.3%) of the patients which detected by DSA. Conclusion: arterial stenosis is more common than cerebral aneurysms and AVM in the patients who subjected to DSA. The presence of hypertension and diabetes mellitus were found to be significantly more prevalent among patients with arterial stenosis. However, the prevalence of hypertension and smoking were more prevalent in cerebral aneurysms.