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18245

Effect of Aloe vera extract on some physiological parameters in diabetic albino rats.

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Last updated: 30 Jan 2023

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Abstract

The present study aimed to clarify antidiabetic activity of aqueous extract from Aloe vera on thirty adult male albino rats were divided into three groups, the first served as a control group, the second was injected with alloxan (120mg / kg B.wt. ) and served as diabetic group and the third was injected with alloxan and treated with Aloe vera water extract ( 0.5 ml / 100 g B.wt. ). After thirty days of treatment half of each group were scarified and the other one were left for 15 days without any additional treatment as a recovery period . The results revealed highly significant decrease ( p> 0.01) in blood glucose, and highly significant increase in both liver glycogen content and serum insulin level in the diabetic group treated with aqueos extract of A. vera when compared with the diabetic untreated group. It seems, therefore that water extract of A. vera results in a definite hypoglycemic, hyperinsulinemic effect. On the other hand, a significant increase of body weight gain and liver glycogen content was achieved. The results of this study clarify the role of Aloe vera active as antidiabetic plant and suggest a relationship between drenching. A. vera extract and insulin production which needs further investigation .  

DOI

10.21608/ejhm.2003.18245

Keywords

Aloe vera – Diabetic rats – Physiological parameters

Authors

First Name

Eman G.E.

Last Name

Helal

MiddleName

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Affiliation

Dept. of Zool., Fac. of Sci, Al-Azhar Univ.

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First Name

Mohamad H.A.

Last Name

Hasan

MiddleName

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Affiliation

Dept. of Phys., Fac. of Med., Menofeyah Univ.

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Orcid

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First Name

Anwaar

Last Name

Al-Kamel .

MiddleName

-

Affiliation

Dept. of Zool., Fac. of Sci, Al-Azhar Univ

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Orcid

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First Name

Ashraf M.

Last Name

Mustafa

MiddleName

-

Affiliation

Dept. of Hist. Fac. of Med., Al-Azhar Univ .

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Volume

12

Article Issue

1

Related Issue

3796

Issue Date

2003-04-01

Receive Date

2018-11-02

Publish Date

2003-04-01

Page Start

53

Page End

61

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 12_Issue 1_Pages 53-61.pdf

PDF . 331.3kB

Link

https://ejhm.journals.ekb.eg/article_18245.html

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https://ejhm.journals.ekb.eg/service?article_code=18245

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6

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

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Article

Created At

22 Jan 2023