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18187

Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.

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Last updated: 03 Jan 2025

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Abstract

Plasma retinol, alpha tocopherol, total cholesterol and triglycerides were measured in 40 patients aged 27-65 years, under regular hemodialysis (HD) for 1.8-13 years at Ahmed Maher teaching Hospital and in 28 healthy age and sex matched control. Predialysis and postdialysis measurements were also, done for a subset of 13 hemodialytic patients. Among hemodialytic patients ,all values ( Plasma retinol ,alpha- tocopherol, total cholesterol and triglycerides )were significantly higher ( p < 0.05 ) with respect to healthy control .The ratio of retinol to total cholesterol was significantly higher , while alpha-tocopherol to total cholesterol ratio was insignificant .In almost all hemodialytic patients, plasma retinol was at toxic level (> 100 ug /dl) except for one patient . On the other hand ,alpha-tocopherol level in hemodialytic patients was ranged between deficiency (<650 ug/dl ) in about 6 (15%) of them , marginal level (650-860 ug/dl ) at 3 ( 8% ) , while 9 (23%) had normal level (860-1080ug/ dl) and the rest 22 (54% ) were in the optimum level (> 1080 ug/dl). Comparing predialysis and postdialysis measurements , the hemodialytic patients showed non significant difference concerning retinol level , while alpha tocopherol was significantly decreased in postdialytic state .In conclusion ; further studies are needed to answer, if hemodialytic patients are at risk for symptomatic vitamin A toxicity?. Even with normal or low plasma vitamin E, it is needed as an antioxidant accessory therapy in hemodialytic patients.  

DOI

10.21608/ejhm.2004.18187

Keywords

Hemodialysis, retinol, alpha-tocopherol, triglycerides total cholesterol

Authors

First Name

Awatif M.

Last Name

Abd El Maksoud

MiddleName

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Affiliation

Clinical Nutrition Department, National Nutrition Institute.

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First Name

Asmaa M

Last Name

. Abd Allah

MiddleName

-

Affiliation

Clinical Nutrition Department, National Nutrition Institute.

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City

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Orcid

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First Name

Mervat A.

Last Name

Ismail

MiddleName

-

Affiliation

Clinical Nutrition Department, National Nutrition Institute.

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City

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Orcid

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First Name

Waleed

Last Name

Massoud

MiddleName

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Affiliation

Nephrology Department ,Ahmed Maher Teaching Hospital.

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Volume

15

Article Issue

1

Related Issue

3782

Issue Date

2004-04-01

Receive Date

2018-11-01

Publish Date

2004-04-01

Page Start

65

Page End

71

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 15_Issue 1_Pages 65-71.pdf

PDF . 322.1kB

Link

https://ejhm.journals.ekb.eg/article_18187.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=18187

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.

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Article

Created At

22 Jan 2023