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Antidiabetic effect of an aqueous extract of Pomegranate (Punica granatum L.) peels in normal and alloxan diabetic rats

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Last updated: 03 Jan 2025

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Abstract

Hypoglycaemic drugs are either too expensive or have undesirable side effects including hematological, coma and disturbances of liver and kidney.
Limiting of diabetes without any side effects is still a challenge to the medical system. This leads to exert effort to search for effective, safer and less cost antidiabetic plants. This investigation aims to evaluate the role of Punica granatum powder peels extract in its human therapeutic dose on beta cell numbers blood glucose and plasma insulin levels in normal and alloxan diabetic rats for 4-weeks of treatment. The treatment revealed that pomegranate aqueous extract significant decreased blood glucose and increased insulin levels in normal and diabetic treated rats. Pancreas showed increased number of beta cells in normal and treated diabetic rats. In conclusion pomegranate peel aqueous extract can reduce blood sugar through regeneration of ß cells.

DOI

10.21608/ejhm.2004.18177

Authors

First Name

Enas A. M.

Last Name

Khalil

MiddleName

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Affiliation

National Organization For Drug Control And Research

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Volume

16

Article Issue

1

Related Issue

3781

Issue Date

2004-07-01

Receive Date

2018-11-01

Publish Date

2004-07-01

Page Start

92

Page End

99

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 16_Issue 1_Pages 92-99.pdf

PDF . 451.3kB

Link

https://ejhm.journals.ekb.eg/article_18177.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=18177

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7

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Antidiabetic effect of an aqueous extract of Pomegranate (Punica granatum L.) peels in normal and alloxan diabetic rats

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Article

Created At

22 Jan 2023