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18056

Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis

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Last updated: 03 Jan 2025

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Abstract

Plasma histamine and serotonin concentrations were measured using fluorimeteric assay in 40 children with renal diseases. Minimal change nephrotic syndrome (15) focal segmental glomerulosclerosis(10) and acute poststreptococcal glomerulonephritis(15) to determine the relation between plasma levels of histamine and serotonin and these various types of renal diseases in children. Plasma histamine level was significantly increased in group of children with acute poststreptococcal glomerulonephritis. Plasma serotonin levels were significantly increased in all 3 groups of patient, when compared with those of controls. Raised plasma histamine in acute poststreptococcal glomerulonephritis group may be evidence of the acute immunological inflammation and defective renal excretion due to mild renal impairment in these children. Raised plasma serotonin in all 3 groups of patients may be due to diminished uptake and release of serotonin from platelets in children with minimal change nephrotic syndrome and focal segmental glomerulosclerosis and due to defective renal execretion in children with acute poststreptococcal glomerulo-nephritis.

DOI

10.21608/ejhm.2005.18056

Authors

First Name

Nagwa

Last Name

Mohamed

MiddleName

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Affiliation

Child handicapped Center

Email

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City

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Orcid

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First Name

Talaat

Last Name

El sayed

MiddleName

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Affiliation

Faculty of Science AlAzhar University

Email

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City

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Orcid

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Volume

21

Article Issue

1

Related Issue

3769

Issue Date

2005-10-01

Receive Date

2018-10-31

Publish Date

2005-10-01

Page Start

139

Page End

144

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 21_Issue 1_Pages 139-144.pdf

PDF . 205.8kB

Link

https://ejhm.journals.ekb.eg/article_18056.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=18056

Order

12

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis

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Article

Created At

22 Jan 2023