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18094

Effect of Licorice on Wound Healing In Rabbits

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Last updated: 24 Dec 2024

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Abstract

Licorice (Glycyrrhiza glabra) is one of the most widely used medicinal plants and is included in numerous traditional and modern medical preparations. In the present study the healing effect of licorice extract was investigated on open skin wounds in rabbits. Adult Newzeland rabbits of both sexes weighing 1.5 - 2.5 kg were used. Hairs of lower back and left flank of animal were shaved. Full-thickness wound (15x15 mm) was made on the shaved area. Hydroalcoholic extract of licorice was prepared by maceration method. Creams of 5%, 10% and 15% (w/w) extract in eucerin base were prepared and applied 2 times daily. Dexpanthenol ointment was used as standard control. Healing was determined by reduction in wound area. The results of this study proved that licorice cream of 10% was a potent healing agent even better than dexpanthenol cream.

DOI

10.21608/ejhm.2005.18094

Authors

First Name

Alsayed, A.

Last Name

Zaki

MiddleName

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Affiliation

Departments of Pharmacology, Faculties of Medicine Cairo Branche, Al-Azhar University

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First Name

Mohammed, H.

Last Name

El-Bakry

MiddleName

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Affiliation

Departments of Pharmacology, Faculties of Medicine Assiut Branche, Al-Azhar University

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Orcid

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First Name

Alaa, A.

Last Name

Fahmy

MiddleName

-

Affiliation

Department of Anatomy, Faculty of Medicine, Ain Shams University , Cairo, Egypt

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Volume

20

Article Issue

1

Related Issue

3768

Issue Date

2005-07-01

Receive Date

2018-10-31

Publish Date

2005-07-01

Page Start

58

Page End

65

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 20_Issue 1_Pages 58-65.pdf

PDF . 254.0kB

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https://ejhm.journals.ekb.eg/article_18094.html

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https://ejhm.journals.ekb.eg/service?article_code=18094

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7

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Effect of Licorice on Wound Healing In Rabbits

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Article

Created At

22 Jan 2023