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18113

The Protective Effect of Vitamin C on Irradiated Testes of Albino Rat.

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Last updated: 24 Dec 2024

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Abstract

The increased exposure to radiation in medicine or industries increases the hazards of radiation on various organs of the human body. The aim of this work was to evaluate the protective effect of anti oxidant (vitamin C) against the effect of radiation on rat testes. Thirty adult albino rats were divided into three groups, each contained ten rats .The first group (G.1) was exposed to 415 r (G.1') or 622 r (G.1") using x-ray source for one minute per day for one week. The second group (G.2) was exposed to 415 r (G.2') or 622 r (G.2") using x- ray source for one minute per day for one week, in addition to vitamin C equivalent to 86.9 mg./liter orally for the two sub groups for the same period . The third group (G.3) was a control group. The examined testes of G.1 showed damaged germinal epithelium with remaining some layers of spermatogonia. There was no affection of spermatocytes, mature sperms, Sertoli cells and Leydig cells, the lumen contained little sperms and debris of germ cells (G.1') .While for (G.1") there was marked damage of the seminiferous tubules with irregular outline, destruction of spermatogonia, spermatocytes and spermatids with pyknotic type of nuclear degeneration and the lumen was devoid of mature sperms. The examined testes of the (G.2) showed evidence of almost complete recovery for G .2' and marked recovery for G.2" It is concluded that anti oxidants were essential to patients exposed to x-ray , to guard against its hazards.

DOI

10.21608/ejhm.2005.18113

Authors

First Name

Lotfy

Last Name

Sayed

MiddleName

-

Affiliation

Departments of Anatomy and Histology, Faculty of Medicine, ALAZHAR University

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Orcid

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First Name

Esam Eldin

Last Name

Abdel Hady

MiddleName

-

Affiliation

Departments of Anatomy and Histology, Faculty of Medicine, ALAZHAR University

Email

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City

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Orcid

-

First Name

Hosam Eldin

Last Name

Hussin

MiddleName

-

Affiliation

Departments of Anatomy and Histology, Faculty of Medicine, ALAZHAR University

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City

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Orcid

-

First Name

Atef

Last Name

Ibrahim

MiddleName

-

Affiliation

Departments of Anatomy and Histology, Faculty of Medicine, ALAZHAR University

Email

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City

-

Orcid

-

First Name

Ola

Last Name

Abdelhamid

MiddleName

-

Affiliation

Anatomy Department, Faculty of Medicine, ALAZHAR University (Girls)

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Volume

19

Article Issue

1

Related Issue

3767

Issue Date

2005-04-01

Receive Date

2018-10-31

Publish Date

2005-04-01

Page Start

92

Page End

100

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 19_Issue 1_Pages 92-100.pdf

PDF . 635.4kB

Link

https://ejhm.journals.ekb.eg/article_18113.html

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https://ejhm.journals.ekb.eg/service?article_code=18113

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

The Protective Effect of Vitamin C on Irradiated Testes of Albino Rat.

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Article

Created At

22 Jan 2023