Beta
18024

Leptin Level and Plasma Prothrombotic Factors in Obese Subjects

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

-

Abstract

Obesity is associated with increased cardiovascular morbidity and mortality. Abnormalities in coagulation and haemostasis represent a well-known link between obesity and thrombosis (both arterial and venous). In human, production of a depocyte-derived peptide, leptin has been linked to adiposity; recent studies have shown that plasminogen activator inhibitor-1 (PAI-1),a prothrombotic factor associated with atherosclerosis complication is also produced in adipose tissue.
Several studies reported that obese subjects had elevated levels of vonWillbrand factor (vWF) and fibrinogen .
The aim of this work is to examine the relationship of obesity, fat distribution and serum leptin concentration with plasma levels of Prothrombotic factors (PAI-1 ā€“ (vWF) and fibrinogen) and lipid pattern (Triglycerides and Cholesterol) as metabolic parameters.
The body fat distribution was evaluated by measuring the body mass index ( BMI) and waist-to- hip ratio (WHR).

DOI

10.21608/ejhm.2006.18024

Authors

First Name

Hamdia

Last Name

Ezzat

MiddleName

-

Affiliation

Clinical Pathology Department, Al-Azhar and Assiut University

Email

-

City

-

Orcid

-

First Name

)Eman M

Last Name

Abd El-Rahman

MiddleName

-

Affiliation

Internal Medicine Department, Al-Azhar and Assiut University

Email

-

City

-

Orcid

-

First Name

Sabilah G

Last Name

Mousa

MiddleName

-

Affiliation

Internal Medicine Departments, Al-Azhar and Assiut University

Email

-

City

-

Orcid

-

First Name

Eman A

Last Name

Mahmoud

MiddleName

-

Affiliation

Rheumatology & Rehabilitation Departments, Al-Azhar and Assiut University

Email

-

City

-

Orcid

-

Volume

22

Article Issue

1

Related Issue

3739

Issue Date

2006-01-01

Receive Date

2018-10-31

Publish Date

2006-01-01

Page Start

39

Page End

48

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_18024.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=18024

Order

4

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Leptin Level and Plasma Prothrombotic Factors in Obese Subjects

Details

Type

Article

Created At

22 Jan 2023