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17791

Clinical comparative study between Magnesium sulphate versus Rocuronium versus Dexmedetomidine as adjuvants for local anesthetic in peribulbar block for eye surgeries

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Last updated: 24 Dec 2024

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Abstract

Background: Regional anesthesia is a preferred technique for ophthalmic surgery. It is safe, inexpensive and provides efficient ocular anesthesia for ophthalmic surgery. It is associated with less hemodynamic instability, less respiratory depression, better postoperative pain relief, and less nausea and vomiting compared to general anesthesia.
Objectives: The aim of the study was to compare the safety and efficacy of the use of Magnesium sulfate versus that of Rocuronium versus Dexmedetomidine as an adjuvant to the local anesthetic in peribulbar anesthesia. It is characterized by generating optimal operating conditions for eye surgery in terms of akinesia, analgesia, incidence of complications, as well as induction of patient and surgeon satisfaction.
Patients and Methods: The present study included100 patients of the American Society of Anesthesiology (ASA), physical status I, II, III or IV of both sex, (20-80) years old and undergoing to anterior and posterior segment surgeries. Informed written consent from all patients was taken after approval of Al-Azhar University Ethical Committee.
Results: Evaluation of the globe akinesia was done at (2.5),(5),(7.5),and(10) min. after injection. The onset of motor block showed a statistically significant difference between the four groups, the rocrounium group showed more rapid onset of motor block then dexmedtomedine group then magnisum sulphate group then lastly the control group.
Conclusion: The present study concluded that using Rocuronium as an additive to local anathestic drugs in peribublar block it makes onset of block more rapid and dense but it has less effect on analgesic aspect. On the other hand, when Dexmedetomidine or Magnesium sulfate were used as additive they increased analgesic effect of local anathestic and decreased the need for early postoperative rescue analgesia, as well as fastening the onset of block but to a lesser extent less than Rocuronium as an additive to local anathestic.

DOI

10.21608/ejhm.2018.17791

Keywords

Magnesium sulphate, Rocuronium, Dexmedetomidine, local anesthetic, peribulbar block, eye surgeries

Authors

First Name

Sayed Ahmad

Last Name

AbdAlali

MiddleName

-

Affiliation

Department of Anesthesiology and Intensive care,Faculty of medicine, Al-Azhar University

Email

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City

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Orcid

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First Name

Gamal Farouk

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Anesthesiology and Intensive care,Faculty of medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Amr Soliman

Last Name

AbdAlmagid

MiddleName

-

Affiliation

Department of Anesthesiology and Intensive care,Faculty of medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Mahmoud Alsayed Hussin

Last Name

Desoki

MiddleName

-

Affiliation

Department of Anesthesiology and Intensive care,Faculty of medicine, Al-Azhar University

Email

mahmoudalsayed39@gmail.com

City

-

Orcid

-

Volume

73

Article Issue

8

Related Issue

3731

Issue Date

2018-10-01

Receive Date

2018-10-28

Publish Date

2018-10-01

Page Start

7,204

Page End

7,210

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 73_Issue 8_Pages 7204-7210.pdf

PDF . 545.3kB

Link

https://ejhm.journals.ekb.eg/article_17791.html

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https://ejhm.journals.ekb.eg/service?article_code=17791

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2

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Clinical comparative study between Magnesium sulphate versus Rocuronium versus Dexmedetomidine as adjuvants for local anesthetic in peribulbar block for eye surgeries

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Type

Article

Created At

22 Jan 2023