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17668

Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus

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Last updated: 24 Dec 2024

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Abstract

Introduction: Lichen planus (L.P) is an idiopathic inflammatory disease of the skin and mucous membrane.
Desmosomes are responsible for the adhesion of keratinocytes. Tonofilaments are one of the major cytoskeleton structure in mammalian epidermis.
Patients and Methods: Six patients complained from Lichen planus are included in this study for the study of ultrastructure of both desmosomes & tonofilaments .
Results: revealed an increase in the size and numbers of both of them which can be explained as a one of the defensive mechanism of the cells against frequent rubbing which is accompanied L.P. which is considered as a resistance mechanism of keratinocytes.

DOI

10.21608/ejhm.2007.17668

Authors

First Name

Sawsan Khalifa

Last Name

EL- Sayed

MiddleName

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Affiliation

Department of Dermatology and Venereology, Al- Azhar University for Girl, Cairo

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First Name

Hossam El- Dein Hussin

Last Name

Osman

MiddleName

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Affiliation

Anatomy Department, Al- Azhar University for Boys, Cairo

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Volume

28

Article Issue

1

Related Issue

3713

Issue Date

2007-07-01

Receive Date

2018-10-26

Publish Date

2007-07-01

Page Start

363

Page End

370

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 28_Issue 1_Pages 363-370.pdf

PDF . 935.1kB

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https://ejhm.journals.ekb.eg/article_17668.html

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https://ejhm.journals.ekb.eg/service?article_code=17668

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus

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Article

Created At

22 Jan 2023