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17563

Effect of Some Slimming Drugs on Some Biochemical and Physiological Parameters of Albino Rats

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Last updated: 24 Dec 2024

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Abstract

 Background:The slimming drugs differ in their nature, where apple-lite is a fully natural substance, mirapro-N is a chemical substance and tenuate is a synthetic foamy filler substance. The study aimed to search the physiological and biochemical changes accompanied  with these drugs on rats.  Methods:Forty adult male albino rats (130±20g) were divided into four groups, ten on each treated group and ten for the control one. The  apple-lite group treated with 3.5mg/100 g body weight, the  mirapro-N group treated with 0.14mg/100g body weight and the  tenuate group treated with 0.1 mg/100 g body weight.  Results: The treated  groups showed a significant changes in the lipid and protein profiles, enzymatic activities, in the skin folds and the percentage of body weight compared to the control group.  In conclusion, the slimming drugs showed a change in skin folds thickness  and in percentage of organ's weight to body weight and also showed a deflection in the investigated biochemical parameters.  

DOI

10.21608/ejhm.2009.17563

Keywords

Slimming drugs, tenuate, apple-lite, mirapro-N, Lipid profile, liver function, skin folds

Authors

First Name

Eman G.E.

Last Name

Helal

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Affiliation

Zoology dep., Faculty of Science, Al-Azhar University, Egypt

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First Name

Ali A.

Last Name

Shati

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Affiliation

Life Science Dep., Faculty of Science, King Khalid University, KSA.

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Orcid

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First Name

Fahmy G.

Last Name

Elsaid

MiddleName

-

Affiliation

Zoology Dep., Faculty of Science, Mansoura University, Egypt.

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Volume

35

Article Issue

1

Related Issue

3687

Issue Date

2009-04-01

Receive Date

2018-10-25

Publish Date

2009-04-01

Page Start

246

Page End

253

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 35_Issue 1_Pages 246-253.pdf

PDF . 787.7kB

Link

https://ejhm.journals.ekb.eg/article_17563.html

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https://ejhm.journals.ekb.eg/service?article_code=17563

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Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Effect of Some Slimming Drugs on Some Biochemical and Physiological Parameters of Albino Rats

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Article

Created At

22 Jan 2023