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17385

Total IgE and Absolute Eosinophils Count as a Predictor of Allergic Diseases in Children

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Last updated: 03 Jan 2025

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Abstract

Objective: To study the role of both serum total IgE levels and the absolute eosinophils count, total IgE alone, absolute eosinophils count alone as a marker of allergy in children, and to see their association with the host factors (age and sex) Methods: A retrospective study was conducted at King Abdul Aziz University Hospital ā€“ Jeddah (KAUH), during the year 2008. Three hundred children below the age of fifteen years meeting the inclusion criteria were enrolled for the study. Serum total IgE levels and absolute eosinophils count were done in all patients. Data was collected and tabulated. Chi-square was applied to test the association of the variables using SPSS and p-value of <0.05 was taken as statistically significant. Results: Out of 300 patients, 27(9%) had raised both serum total IgE and absolute eosinophils count, 146(48.67%) had raised serum total IgE alone, 40(13.3%) had raised absolute eosinophils count alone. Both IgE plus absolute eosinophilic count, total IgE alone and absolute eosinophilic count alone are not significantly related to the child sex with (P-values 0.759, 0.742, 0.699) respectively, however all are related significantly to the child age (P-values <0.004, <0.001, <0.012) respectively. All are not related significantly to systemic allergies except the significant relation between the absolute eosinophils count with atopic dermatitis (P- value <0.031) Conclusion: Serum total IgE level and absolute eosinophils count, total IgE alone and absolute eosinophils count alone are not a good predictor of allergy in children except that the absolute eosinophils count can be considered as a strong predictor of atopic dermatitis in children. It's clear now, that as the child age increase the positivity of all the tests increase also.

DOI

10.21608/ejhm.2010.17385

Authors

First Name

Hamid

Last Name

Habib

MiddleName

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Affiliation

Consultant Pediatrician, Dean Faculty of Medicine ā€“ Rabigh - King Abdul Aziz University (KAU)

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Orcid

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First Name

Moufag

Last Name

Tayeb

MiddleName

-

Affiliation

Assistant Professor Faculty of Medicine - Rabigh - KAU.

Email

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City

-

Orcid

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First Name

Majdy

Last Name

Qutub

MiddleName

-

Affiliation

Consultant Family Physician, King Abdul Aziz University Hospital.

Email

-

City

-

Orcid

-

First Name

Jamil

Last Name

Samkari

MiddleName

-

Affiliation

Consultant Family Physician, King Abdul Aziz University Hospital.

Email

-

City

-

Orcid

-

First Name

Abdulrahman

Last Name

Abu Dawood.

MiddleName

-

Affiliation

Demonstrator Faculty of Medicine - Rabigh ā€“ KAU.

Email

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Orcid

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Volume

40

Article Issue

1

Related Issue

3652

Issue Date

2010-07-01

Receive Date

2018-10-23

Publish Date

2010-07-01

Page Start

365

Page End

374

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 40_Issue 1_Pages 365-374.pdf

PDF . 466.3kB

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https://ejhm.journals.ekb.eg/article_17385.html

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https://ejhm.journals.ekb.eg/service?article_code=17385

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6

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Total IgE and Absolute Eosinophils Count as a Predictor of Allergic Diseases in Children

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Article

Created At

22 Jan 2023