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16949

Anti-müllerian hormone, inhibin B and antral follicle count as markers of premature ovarian failure in women with type I diabetes mellitus

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Last updated: 24 Dec 2024

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Abstract

Objective: To evaluate the different markers of ovarian reserve (AMH-Inhibin B , FSH and antral follicle count (AFC) in insulin dependent diabetes mellitus ( IDDM). Methods: We studied 30 patients with IDDM as study groups (10cases>32 years group IV and 20 cases 32 years group II) and 20 healthy women as control groups (8 cases >32 years group III and 12 cases 32 years group I . Serum levels of FSH, LH, inhibin B and AMH were measured at (days 1-7) of menstrual cycle and AFC was done by trans vaginal ultrasound. Results: AMH levels were lower in IDDM patients than in controls > 32 years (2.35 2.2 versus 7.79
difference in the levels of FSH .. AFC is valuable for the diagnoses of premature ovarian failure in IDDM.
1.73 p0.000). Also IDDM groups showed lower levels of inhibin B. While there is no Conclusion: Compared with FSH (AMH and inhibin B) are more valuable for the diagnosis of premature ovarian aging in IDDM patients which developed earlier decline in the ovarian follicle pool compared with the healthy women and also AMH is more valuable than AFC for detection of premature ovarian failure in IDDM.

DOI

10.21608/ejhm.2010.16949

Authors

First Name

Alshimaa A .

Last Name

Abd Elatif

MiddleName

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Affiliation

Gynecology and obstetric Al Azhar University, Faculty of Medicine for Girls.

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First Name

Sabah I .

Last Name

Abd Elreheem

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Affiliation

Clinical pathology Al Azhar University, Faculty of Medicine for Girls.

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First Name

Amany M. E .

Last Name

Abd Elmegeed

MiddleName

-

Affiliation

Clinical pathology Al Azhar University, Faculty of Medicine for Girls.

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First Name

Hoda Mahmoud

Last Name

Abd El Wahab

MiddleName

-

Affiliation

Radiodiagnostic Departments, Al Azhar University, Faculty of Medicine for Girls.

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Volume

41

Article Issue

1

Related Issue

3581

Issue Date

2010-10-01

Receive Date

2018-10-19

Publish Date

2010-10-01

Page Start

502

Page End

514

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_16949.html

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https://ejhm.journals.ekb.eg/service?article_code=16949

Order

4

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Anti-müllerian hormone, inhibin B and antral follicle count as markers of premature ovarian failure in women with type I diabetes mellitus

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Article

Created At

22 Jan 2023