Aim of the work:the present study was carried out to investigate the possible ameliorating effects of three herbs: hops(H) 1.5g/kg diet , rosemary(R) 5g/kg diet  and cat's claw (C C) 1.7g/kg diet on hepatic toxicity induced by 7,12-Dimethyl benz(A)antheracene , a hydrocarbon  involves various negative consequence for human health and ecosystems conversation .Results:in this work,48 female rats at 50 day of age were divided into 8 groups; control ,hops(H), rosemary(R), cat^'s claw(CC),DMBA, DMBA+H,DMBA+R and DMBA+CC groups.Results:the results indicated that a single intraperitonial  (i.p) dose of DMBA (30mg/Kg b.W) caused significant decrease in the percentage of body weight  gain, but an increase in the hepatosomatic  index. In addition , the results illustrated an increase in the liver malondialdehyde (MDA) contents and hydrogen peroxide levels (H₂O₂) accompanied by significant decrease in reduced glutathione (GSH) content and superoxide dismutase (SOD) and glutathione-S-transferase (GST) activities.The results, also  reported significant decrease in serum total proteins,  total albumin ,  globulin  and liver total protein but serum total bilirubin was significantly elevated in the DMBA intoxicated group. Furthermore, aspartate aminotransaminase (ASAT), alanine aminotransaminase (ALAT) , γ-glutamyltransferase (GGT) and alkaline phosphatase (ALP) activities were significantly increased in serum but significantly decreased in the liver. On the other hand, intake of  hops, rosemary and cat^'s claw minimize the disturbances observed in most of the tested parameter's resulted from DMBA administration and improve the liver functions mostly in the following order, rosemary ˃  hops ˃ cat's claw. Conclusion: it can be concluded that intake of such herbs (hops , rosemary, cat^'s claw)may be effective in reducing DMBA toxicity.