15813

Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure

Article

Last updated: 03 Jan 2025

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Abstract

Background: Zinc (Zn) deficiency in endothelial cells potentiates the inflammatory response mediated by certain lipids and cytokines, possibly via mechanisms associated with increased cellular oxidative stress. Objectives: To assess the relation between zinc level and one year mortality among elderly patients with heart failure. Patients and Methods: Serum zinc level was measured in 100 elderly patients with heart failure diagnosed by Criteria of New York Heart Association (NYHA). Patients were followed by telephone for one year to assess relation between Zinc level and one year mortality among elderly patients with heart failure. Results: Higher mortality percentage was found among patients with high level of zinc but there was no statistical significant difference. (P-value >0.05). And non significant relation was found between mean level of zinc and mortality, between age and Zn, and between  Ejection Fraction (EF) and Zn. Zn level was lower among patients with EF >45 but the difference was not significant (P-value >0.05). Conclusion: Patients who had high level of zinc had greater risk for mortality. Zn level was lower among patients with EF >45 but the difference was not significant and the least mean of zinc was among patients with left ventricular (LV) systolic dysfunction.  

DOI

10.12816/0002425

Keywords

zinc, mortality, elderly patients, Heart failure

Authors

First Name

Nora Abdel-Khalek

Last Name

Abdel-Salam

MiddleName

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Affiliation

Geriatric Medicine Faculty of Medicine - Ain Shams University

Email

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City

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Orcid

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First Name

Walaa Wessam

Last Name

Aly

MiddleName

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Affiliation

Geriatric Medicine Faculty of Medicine - Ain Shams University

Email

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City

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Orcid

-

First Name

Sarah Ahmed

Last Name

Hamza

MiddleName

-

Affiliation

Geriatric Medicine Faculty of Medicine - Ain Shams University

Email

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City

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Orcid

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First Name

Ahmed Kamel

Last Name

Mortagy

MiddleName

-

Affiliation

Geriatric Medicine Faculty of Medicine - Ain Shams University

Email

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City

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Orcid

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First Name

Hossam Mosfata

Last Name

Fahmy

MiddleName

-

Affiliation

Clinical Pathology Faculty of Medicine - Ain Shams University

Email

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City

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Orcid

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Volume

54

Article Issue

1

Related Issue

3410

Issue Date

2014-01-01

Receive Date

2018-10-03

Publish Date

2014-01-01

Page Start

11

Page End

14

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_15813.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=15813

Order

2

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure

Details

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Article

Created At

22 Jan 2023