15594

Is Neutrophil/Lymphocyte Ratio A Useful Marker to Predict the Severity of Pre-Eclampsia?

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Last updated: 03 Jan 2025

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Abstract

Background: Preeclampsia refers to the new onset of hypertension and proteinuria or hypertension and end-organ dysfunction with or without proteinuria after 20 weeks of gestation in a previously normotensive woman. Objective: This study was aimed to evaluate the relationship between Neutrophil/Lymphocyte ratio (NLR) in patients with pre-eclampsia (PE) and severity of preeclampsia. Subjects and methods: This prospective study comprised a total of 150 pregnant females divided in 3 groups "50 healthy pregnant females (Group 1), 50 females with mild pre-eclampsia (Group 2) and 50 with severe pre-eclampsia (Group 3)".All the study participants were statistically compared in respect to Neutrophil/Lymphocyte Ratio (NLR) and the baseline data including age and BMI. Results: Maternal NLR was determined to be significantly high in the pre-eclamptic patients (Groups 2 and 3) compared to those with healthy pregnancies (Group 1) (p = 0.0003).NLR was significantly higher in the severe pre-eclampsia group than in the mild pre-eclampsia group (p = 0.042). Conclusion: It could be concluded that while NLR was determined as significantly high in patients with pre- eclampsia, to be able to use this in the classification of the severity of pre-eclampsia, there is a need for further studies on a more extensive population.

DOI

10.21608/ejhm.2018.15594

Keywords

Leukocytes, Neutrophils, Neutrophil/lymphocyte ratio, Pre-eclampsia

Authors

First Name

M

Last Name

Abd-Alazim

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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Orcid

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First Name

Ashraf H

Last Name

Mohammad

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

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City

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Orcid

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First Name

Mohammad S

Last Name

Radwan

MiddleName

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Affiliation

Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

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City

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Orcid

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First Name

Ahmed A

Last Name

Shokr

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

dr.ah.shoker@gmail.com

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Orcid

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Volume

73

Article Issue

5

Related Issue

3385

Issue Date

2018-10-01

Receive Date

2018-10-01

Publish Date

2018-10-01

Page Start

6,621

Page End

6,625

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_15594.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=15594

Order

5

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Is Neutrophil/Lymphocyte Ratio A Useful Marker to Predict the Severity of Pre-Eclampsia?

Details

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Article

Created At

22 Jan 2023