Aim of the study: To determine the preservative capacity of different cosmetic preparations commonly found in the Egyptian markets. Methods:Microbiological evaluation of 74 cosmetic sample and preservative capacity test for cosmetic samples showing no microbial contamination using rejecting microorganisms by cup plate technique. Results: It was found that 29 samples were contaminated at levels >10³ or >500 (for baby care products) or contaminated with rejecting microorganisms or both. The preservative capacity was variable between the different types and brands of the tested cosmetics against bacteria (P<0.05), while for Candida albicans all samples of the different cosmetic types were of nearly the same effect (p>0.05). Conclusion: The detection of microbial counts greater than the microbial limits standards and isolation of rejecting microorganisms are clear evidences of non-adherence to good Manufacturing Practices. Variable preservative capacity in some cosmetics may indicate its ability to withstand microbial contamination which leads to spoilage of these cosmetics.