13959

Systematic Review: The Burden of Post-operative Complications Following Colectomy for Ulcerative Colitis

Article

Last updated: 03 Jan 2025

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Abstract

Background: Ulcerative colitis (UC) patients failing medical management require colectomy. 
Methods:Literature search in MEDLINE , CINAHL and Embase, targeting studies reporting the outcomes of colorectal procedures (from 2002 to 2016 with total and subtotal colectomy postoperative complications in adults with ulcerative colitis as an endpoint. Texts and authoritative Web sites were also reviewed then identification of papers according to the inclusion and exclusion criteria and data extraction were performed by two independent researchers.
Results:Following data extraction and synthesis, we identified 24 articles for review. Reporting outcomes from procedures conducted from 2002–2016. Most frequent short-term complications: infectious complications and ileus (mean incidence 21% and 19%), while most frequent long-term complications: pouchitis, fecal incontinence and small bowel obstruction (mean incidence 31%, 22% and 18%). Post-operative early complications (≤30 days) occurred in 18–63% of patients with ulcerative colitis while late complications (>30 days) occurred in 19–58% of patients. Rates of early infection and late pouch failure decreased significantly from 2002 to 2015 (22% to 2% respectively).
Conclusion:although Colectomy remains an appropriate therapeutic strategy for specific groups of patients- it is not the optimal cure for UC. Clinicians need to fully understand the various postoperative complications and comorbidities that are highly prevalent with over a third of patients expected to experience long-term or late arising post-operative complications. Thus, while surgical procedures are recommended as an appropriate therapeutic strategy for a specific group of patients, the post-operative complications associated with these surgical procedures should not be underestimated.
 

Keywords

ulcerative colitis, post-operative complications, colectomy, pouchitis, colon surgery

Authors

First Name

Bandar Kamal Mufreh

Last Name

Alsirhani

MiddleName

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Affiliation

University Of Gezira

Email

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City

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Orcid

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First Name

MasadMasaeedMasad

Last Name

Almutairi

MiddleName

-

Affiliation

University Of Gezira

Email

-

City

-

Orcid

-

First Name

SaadMunawwikh

Last Name

Alshammari

MiddleName

-

Affiliation

Lublin Medical University

Email

-

City

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Orcid

-

First Name

Abdulraouf Mohammad

Last Name

Altaleb

MiddleName

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Affiliation

King Abdulziz University

Email

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City

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Orcid

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First Name

Othman Rushdy

Last Name

Filfilan

MiddleName

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Affiliation

Umm Al-Qura University

Email

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City

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Orcid

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First Name

Mohammed Abdulaziz

Last Name

Othman

MiddleName

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Affiliation

King Abdulziz University

Email

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City

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Orcid

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First Name

Mohammed Seror

Last Name

Bawahal

MiddleName

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Affiliation

King Abdullah Hospital

Email

bawhal_01@yahoo.com

City

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Orcid

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First Name

Abdullah Hussain

Last Name

Muzaffar

MiddleName

-

Affiliation

Umm Al-Qura University

Email

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City

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Orcid

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Volume

67

Article Issue

1

Related Issue

2711

Issue Date

2017-04-01

Receive Date

2018-09-17

Publish Date

2017-04-01

Page Start

285

Page End

293

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_13959.html

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https://ejhm.journals.ekb.eg/service?article_code=13959

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Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Systematic Review: The Burden of Post-operative Complications Following Colectomy for Ulcerative Colitis

Details

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Article

Created At

22 Jan 2023