13580

Male Breast Cancer: A Retrospective Study

Article

Last updated: 03 Jan 2025

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Abstract

Background: The male breast cancer (MBC) is a rare disease and represents less than 1% of all malignancies in men and less than 1% of all breast cancers incident. Aim of study: In this descriptive retrospective study we aimed to provide clinico-epidemiological characteristics of MBC. To present the treatment given with respect to DFS , TTP & OS, to identify possible prognostic factors of the disease and the toxicities encountered by the treatment given. Patients and Method:  Out of 11313 cancer patients 3046 were breast cancer; 28 of them were MBC. All patients presented to clinical oncology department in Ain Shams University in the period from January 2008 to December 2014 and follow up till December 2016 Results: The median age of patients was 59 years. Around 90% had hormone receptor positive (estrogen and/or progesterone receptors).Two third of the patients had advanced T-stage (T3 and T4). Infiltrating ductal carcinoma the most common type of histology was encountered. Modified radical mastectomy was the most common (75%) type of surgery done followed by chemotherapy for 21 patients and loco-regional radiotherapy for 20 patients. Tamoxifen was administered in 19 patients. Relapse occurred in 14 patients (50%). The 5-year disease-free survival (DFS) was 21.4%, the 5-year time to progression (TTP) rate was 21.4% and the 5-year old overall survival (OS) rate was 35.7%. Conclusion: There is always a delay in the male patients since the first complaint until they seek medical advice, which results in an advanced disease at presentation.  

DOI

10.12816/0039667

Keywords

Male breast cancer, Female breast cancer, BRCA gene, tamoxifen, Aromatase inhibitor

Authors

First Name

Hatem Mohamed

Last Name

Abdallah

MiddleName

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Affiliation

Clinical oncology department, Ain Shams University

Email

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City

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Orcid

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First Name

Ramy Refaat Youssef

Last Name

Ghali

MiddleName

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Affiliation

Clinical oncology department, Ain Shams University

Email

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City

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Orcid

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First Name

Mai Mohamed Ali

Last Name

Ezz El Din

MiddleName

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Affiliation

Clinical oncology department, Ain Shams University

Email

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City

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Orcid

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First Name

Hesham Mahmoud

Last Name

Elshimy

MiddleName

-

Affiliation

Clinical oncology department, Ain Shams University

Email

drelshimyhesham@gmail.com

City

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Orcid

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Volume

68

Article Issue

3

Related Issue

2617

Issue Date

2017-07-01

Receive Date

2018-09-13

Publish Date

2017-07-01

Page Start

1,308

Page End

1,315

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_13580.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=13580

Order

2

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Male Breast Cancer: A Retrospective Study

Details

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Article

Created At

22 Jan 2023