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12977

Clinical Short-Term Outcome of Severe Untreated Aortic Stenosis

Article

Last updated: 03 Jan 2025

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Abstract

Background: sclerocalcific aortic valve is a common condition. Risk stratification and decision making are particularly complex in adults with aortic stenosis (AS), because the disease mainly affects elderly patients who represent a heterogeneous population and require balanced and individualized analysis using a multidisciplinary collaboration. Further research is needed to provide better evidence in particular on spontaneous risk, earlier detection of LV dysfunction, and the results of transcatheter treatment and medical therapy. Objectives: to study the clinical short term outcome of the severe untreated severe sclerocalcific aortic valve stenosis and also to evaluate the correlation between echocardiography assessment of aortic stenosis and clinical history and examination. Methods: in our study of 50 patients with severe sclerocalcific aortic stenosis, were subjected to full history taking along with full clinical examination and transthoracic echocardiography at baseline and follow up. The TTE criteria for diagnosis of severe Sclerocalcific aortic stenosis are increased echogenicity and thickening of the aortic valve leaflets with mean gradient greater than 40 mm Hg, and maximum jet velocity greater than 4 m per second, valve area less than 1.0 cm2. Results: at short term follow up of our patients (2 years), there were significant increase in the number of patients who developed symptoms of angina and heart failure (p<0.01) but there was no statistically significant increase in those who develop syncope (P=0.106). There were very evident echocardiographic findings in the form of highly significant (p<0.01) decrease in the EF & valve area and increase in the MPG, PPG, Max. Jet velocity. Conclusion: 41.2% of previously asymptomatic patient developed symptoms at follow up. There were very evident and significant changes in the echocardiographic findings related to significant decrease in the EF & vave area and increase in the MPG, PPG, Max. jet velocity and intracardiac dimensions that is reflected in the clinical symptoms progression throughout the follow up period.  

DOI

10.12816/0038178

Keywords

Sclerocalcific, Severeaortic stenosis, aortic valve replacement, Ejection fraction – aorticvalve area- Max. Jet velocity-mean pressure gradient

Authors

First Name

Mohsen Fahmy

Last Name

Metwally

MiddleName

-

Affiliation

Department of Cardiology, Ain Shams - Faculty of Medicine

Email

sal.alahwany@gmail.com

City

-

Orcid

-

Volume

68

Article Issue

1

Related Issue

2461

Issue Date

2017-07-01

Receive Date

2018-09-09

Publish Date

2017-07-01

Page Start

806

Page End

814

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_12977.html

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https://ejhm.journals.ekb.eg/service?article_code=12977

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1

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Clinical Short-Term Outcome of Severe Untreated Aortic Stenosis

Details

Type

Article

Created At

22 Jan 2023