Background: Diabetes mellitus (DM) is just one of the world's fastest growing chronic conditions as well as a leading cause of acquired vision loss, diabetic macular edema (DME) is a disease linked to diabetes. Some individuals with diabetes will certainly get a kind of retinopathy-a problem of the retina in the eye. Diabetic retinopathy could progress as well as result in DME (additionally referred to as retinal swelling) that might impact your vision, and is among the most usual reasons for blindness. Objective: In this review we discuss about the most dangerous risk factors during treatment and in daily life, which can worsen the treatment prognosis. Methods: PubMed and Embase database were searched up to July, 2018 for relevant studies that discussing the risk factors of glaucoma. Result: It is clear that the variety of people affected by DM is expanding greatly, as is the variety of patients with problems from DM. Fortunately; the eye symptoms of DME can be identified and managed prior to considerable vision loss happens if patients with DM undergo routine eye tests and much better manage their systemic condition. Conclusion: Close collaboration in between doctors and also ophthalmologists is important in the managing of patients with diabetic retinopathy and also DME. To make certain very early medical diagnosis as well as treatment all diabetic person patients should be screened for diabetic person retinopathy. Control of blood pressure, serum lipids, and also renal function are very important treatments focused on prevention of visual impairment associated with diabetic retinopathy and DME.