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Glasgow Coma Scale in Anticipation of Sepsis and Septic Shock: Review Article

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Last updated: 24 Dec 2024

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Abstract

Evaluation of level of consciousness has become essential for anticipation of sepsis and septic shock. Both the Sequential Organ Failure Assessment (SOFA) score and the quick SOFA score utilize the Glasgow Coma Score (GCS) for screening of sepsis. Objectives: the aim of this review is to determine and study the role of Glasgow coma score in anticipation of sepsis and septic shock. Methods: To achieve this aim, we have searched online database, namely PubMed and Cochrane Library for studies and review articles assessing the significance of assessment of Glasgow Coma Scale (GCS) for anticipating sepsis or septic shock. Thirteen appropriately-related studies were selected for review. Results: Disturbed sensorium was found to be a sensitive early indicator for sepsis, thus GCS is used for assessment of both the Sequential Organ Failure Assessment (SOFA) and quick SOFA scores qSOFA scores. Lower GCS scores were associated with high mortality rates. Discussion: Encephalopathy is an early sign of sepsis and septic shock. Glasgow Coma score (GCS) was a good indicator of neurological dysfunction evaluated by the SOFA and qSOFA scores. The use of GCS was also a predictor of mortality in patients with sepsis. Some researchers, however, reported that GCS was not the best tool for measuring brain dysfunction in sepsis. Conclusions: Glasgow coma score can anticipate sepsis and septic shock, and predict the outcome of sepsis.  

DOI

10.12816/0042245

Keywords

Glasgow Coma score, Sepsis, Septic shock

Authors

First Name

Mohammed Saeed M

Last Name

Alalawi

MiddleName

-

Affiliation

Department of Emergency Medicine,Anak General Hospital, Anak, Saudi Arabia

Email

mohd.s.alawi@gmail.com

City

-

Orcid

-

First Name

Hussain Abdullah M

Last Name

Aljabran

MiddleName

-

Affiliation

Department of Emergency Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Abdullah Mohammed

Last Name

Alkhamri

MiddleName

-

Affiliation

Department of Emergency Medicine, King Saud University, Riyadh, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Abdulrahman Mohammed

Last Name

Alwahbi

MiddleName

-

Affiliation

Department of Emergency Medicine, Qassim University, Qassim, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Zahra Ibrahim

Last Name

AlQarrash

MiddleName

-

Affiliation

Department of Emergency Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Hussain Abdulillah M

Last Name

Iraqi

MiddleName

-

Affiliation

Department of Emergency Medicine, Jeddah University, Jeddah, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Mohammed Saleh M

Last Name

Alonazi

MiddleName

-

Affiliation

Department of Emergency Medicine, Imam Muhammad ibn Saud Islamic University

Email

-

City

-

Orcid

-

First Name

Abdulaziz Raja Najim

Last Name

Alotaibi

MiddleName

-

Affiliation

Department of Emergency Medicine,Taif University, Taif, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Majed Ali Mohammed

Last Name

Alahmari

MiddleName

-

Affiliation

Department of Emergency Medicine, Imam Muhammad ibn Saud Islamic University

Email

-

City

-

Orcid

-

First Name

Ahmed Abdalmuhssen A

Last Name

Alnuwaiser

MiddleName

-

Affiliation

Department of Emergency Medicine, King Faisal University, Hofuf, Saudi Arabia,

Email

-

City

-

Orcid

-

First Name

Feras Khalid A.

Last Name

Mimarji

MiddleName

-

Affiliation

Department of Emergency Medicine, Jeddah University, Jeddah, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Abdullah Atallah

Last Name

Al-Enezi

MiddleName

-

Affiliation

Department of Emergency Medicine, Majmaah University, Al Majmaah, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Naif Ahmed A

Last Name

Alabbad

MiddleName

-

Affiliation

Department of Emergency Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland,

Email

-

City

-

Orcid

-

First Name

Alaa Hassan

Last Name

Alhayki

MiddleName

-

Affiliation

Department of Emergency Medicine, Imam Abdulrahman bin Faisal University, Dammam

Email

-

City

-

Orcid

-

First Name

Mashail Hashim H

Last Name

Farran

MiddleName

-

Affiliation

Department of Emergency Medicine, Ibn Sina National College, Jeddah, Saudi Arabia

Email

-

City

-

Orcid

-

Volume

69

Article Issue

6

Related Issue

2199

Issue Date

2017-10-01

Receive Date

2018-08-30

Publish Date

2017-10-01

Page Start

2,663

Page End

2,666

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 69_Issue 6_Pages 2663-2666.pdf

PDF . 228.4kB

Link

https://ejhm.journals.ekb.eg/article_12031.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=12031

Order

17

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Glasgow Coma Scale in Anticipation of Sepsis and Septic Shock: Review Article

Details

Type

Article

Created At

22 Jan 2023