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Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article

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Last updated: 03 Jan 2025

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Abstract

Over the past few decades, vitamin D was proposed to be highly influential on female fertility and reproductive health. Its role was extensively studied and evaluated specifically in females with polycystic ovarian syndrome. Objectives: the aim of this research was to study the correlation between vitamin D and fertility in general, and in polycystic ovarian syndrome-associated infertility in particular. Methods: we searched Cochrane Library and PubMed for articles addressing the impact and role of vitamin D in fertility issues in females with polycystic ovary disease. Specifically-related topics were carefully reviewed and analyzed to summarize their conclusive results. Results and Discussion: Vitamin D was lower in females with PCOS and vitamin D administration had increased its level, improved metabolic disturbance and shortened inter-menstrual intervals in those patients. Patients with high vitamin D levels had a better success rate of in-vitro fertilization. However, it did not affect the time to pregnancy in PCOS women.  Conclusion: Vitamin D is beneficial for improving metabolic as well as reproductive functions in women with PCOS. It is also essential for successful in-vitro fertilization, and it is probably protective against endometriosis. However, results from different studies are contradictory, and still there is no solid evidence that there is a cause-effect relationship between vitamin D and fertility.    

DOI

10.12816/0042239

Keywords

polycystic ovary, PCO, Vitamin D, fertility

Authors

First Name

Marah Mohammed

Last Name

Alzaidi

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Taif University, Taif

Email

dr.mara7-alzaidi@hotmail.com

City

-

Orcid

-

First Name

Hassan Hamza A

Last Name

Almir

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology Imam Abdulrahman bin Faisal university, Dammam

Email

-

City

-

Orcid

-

First Name

Afraa Qasim Ibrahim

Last Name

Khormi

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Jazan University, Jazan

Email

-

City

-

Orcid

-

First Name

Yassmeen Mohammed

Last Name

Alltaleb

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Alfaisal University, Riyadh

Email

-

City

-

Orcid

-

First Name

Zahra Mohamed A

Last Name

Al Muwais

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Imam Abdulrahman bin Faisal university, Dammam

Email

-

City

-

Orcid

-

First Name

Rehab Abdul Rahman

Last Name

Alsaleh

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Ibn Sina National College, Jeddah

Email

-

City

-

Orcid

-

First Name

Nora Faisal

Last Name

Alsaud

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Alfaisal University

Email

-

City

-

Orcid

-

First Name

Lama Mohammed

Last Name

Alomar

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Almaarefa College for Science and Technology, Riyadh

Email

-

City

-

Orcid

-

First Name

Reema Adnan

Last Name

Shabkah

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology,King Abdulaziz University, Jeddah

Email

-

City

-

Orcid

-

First Name

Abdulrahman Hassan

Last Name

Khormi

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology,king Fahd Central Hospital, Jazan, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Reyhana

Last Name

Safi

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology,Ibn Sina National College, Jeddah

Email

-

City

-

Orcid

-

Volume

69

Article Issue

6

Related Issue

2199

Issue Date

2017-10-01

Receive Date

2018-08-30

Publish Date

2017-10-01

Page Start

2,627

Page End

2,631

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 69_Issue 6_Pages 2627-2631.pdf

PDF . 195.8kB

Link

https://ejhm.journals.ekb.eg/article_12023.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=12023

Order

11

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article

Details

Type

Article

Created At

22 Jan 2023