Beta
ManageSearchChatDiscover
11966

Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Anticoagulation is the mainstay treatment of pulmonary embolism. Using low molecular weight heparin versus unfractionated heparin remains a matter of debate. Objectives: the aim of this review is to study the prognosis of using low molecular weight versus unfractionated heparin in treatment of pulmonary embolism. Methods: PubMed and Cochrane library were searched for articles comparing the efficacy of low molecular weight heparin and unfractionated heparin in management of pulmonary embolism. Ten related results were selected for review. Results: Literatures studies indicated that low molecular weight heparin was effective in therapeutic treatment of acute sub-massive and massive pulmonary embolism. It was as effective as intravenous unfractionated heparin. It was not associated with higher risk of major, minor bleeding, or thrombocytopenia. Low molecular weight heparin was as effective as unfractionated heparin in prophylaxis of deep venous sinus thrombosis as well as pulmonary embolism.  Discussion: Low-molecular-weight heparin seemed to be as effective safe as intravenous unfractionated heparin for the treatment as well as prophylaxis of pulmonary embolism. It was also safe with no major bleeding risk or higher risk of thrombocytopenia. Conclusion: Both low molecular weight and unfractionated heparin had similar efficacy and safety in management of PE.  

DOI

10.12816/0041693

Keywords

pulmonary embolism, low molecular weight heparin, unfractionated heparin, Outcome

Authors

First Name

Abdullah Obaid

Last Name

Binobaid

MiddleName

-

Affiliation

Alfaisal University, Riyadh, Saudi Arabia

Email

abinobaid@alfaisal.edu

City

-

Orcid

-

First Name

Maan Ahmed

Last Name

Alsaaid

MiddleName

-

Affiliation

Arabian Gulf University, Manama, Bahrain

Email

-

City

-

Orcid

-

First Name

Ibrahim Ali I.

Last Name

Alasseri

MiddleName

-

Affiliation

Majardah General Hospital, Abha, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Balgaith H.

Last Name

Albareqi

MiddleName

-

Affiliation

Primary Health Care, Al-Birk, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Kawther Abdulroof

Last Name

Alabbas

MiddleName

-

Affiliation

Al Maarefa Colleges, Riyadh, Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Meryem

Last Name

Safi

MiddleName

-

Affiliation

Ibn Sina National College, Jeddah, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Ali Mohammed A.

Last Name

Alasmari

MiddleName

-

Affiliation

King Fahd Military Medical Complex, Dammam, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Yousef Mohammed

Last Name

Alhazmi

MiddleName

-

Affiliation

Al Amal Mental Health Complex, Jeddah, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Haider Issa

Last Name

Alaqaili

MiddleName

-

Affiliation

Dammam Medical Complex, Dammam, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Fatema Salman Hasan Salman

Last Name

Khalaf

MiddleName

-

Affiliation

October 6th University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Nareman Suliman

Last Name

Shamlan

MiddleName

-

Affiliation

Batterjee Medical College

Email

-

City

-

Orcid

-

First Name

Bashayer Ateya

Last Name

Al-Harthy

MiddleName

-

Affiliation

Taif University, Taif, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Mohannad Abdulrazzaq

Last Name

Alalwan

MiddleName

-

Affiliation

Imam Abdulrahman bin Faisal university, Dammam, Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Adel Mushref Ali

Last Name

Alharban

MiddleName

-

Affiliation

Primary Health Care, Abha, Saudi Arabia

Email

-

City

-

Orcid

-

Volume

69

Article Issue

5

Related Issue

2195

Issue Date

2017-10-01

Receive Date

2018-08-30

Publish Date

2017-10-01

Page Start

2,455

Page End

2,458

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 69_Issue 5_Pages 2455-2458.pdf

PDF . 225.2kB

Link

https://ejhm.journals.ekb.eg/article_11966.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=11966

Order

15

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Prognosis of Unfractioned Heparin versus Low Molecular Weight Heparin in Pumlonary Embolism: Review Article

Details

Type

Article

Created At

22 Jan 2023