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El-Sayed Mohamed El-Habibi; Magda Protective Effect of Date Palm Extracts on Cadmium-Induced Infertility in Male Rats

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Last updated: 03 Jan 2025

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Abstract

Background: Infertility is a problem which affects one in six couples. However, male factor considers solely responsible in about 20% of infertile couples and contributory in another 30–40%. Objective: The aim of this study was to elucidate the effect of date palm pollen (DPP) and date palm seed extract (DPS) on cadmium-induced infertility in male rats. Materials and Methods: Thirty six male albino rats were divided into six groups (n=6) and received their treatment orally for 30 days: group 1, control; group 2, (DPP): (240mg/kg) daily, group 3, (DPS): (100mg/kg) daily, group 4, (CdCl2): (5mg/kg) every other day, group 5, (CdCl2 + DPP): CdCl2 as group 4, followed by DPP as group 2 (each dose given 2 hours after CdCl2); group 6, (CdCl2 + DPS): CdCl2 as group 4, followed by DPS as group 3 (each dose was given 2 hours after CdCl2). Results: The current data exhibited significant decrease in the sperm quality, T, E2, FSH, LH, aromatase enzyme, TAC, GSH, SOD and CAT, with marked increase in MDA& XO and severe destruction in testis histoarchitecture in CdCl2 treated rats. However, there was a significant improvement in all these parameters with DPP& DPS administration. Conclusion: consumption of DPP or DPS might be considered as a functional treatment for retarding risks of infertility associated with cadmium exposure.    

DOI

10.12816/0041514

Keywords

Male infertility, cadmium, date palm pollen, Date palm seed, antioxidants, testis

Authors

First Name

Mahmoud

Last Name

El-Komy

MiddleName

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Affiliation

Physiology Division, Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

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First Name

Heba Osama

Last Name

Saad

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-

Affiliation

Physiology Division, Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

Email

heba_osama2014@hotmail.com

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-

Orcid

-

Volume

69

Article Issue

4

Related Issue

2178

Issue Date

2017-10-01

Receive Date

2018-08-28

Publish Date

2017-10-01

Page Start

2,181

Page End

2,190

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_11852.html

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https://ejhm.journals.ekb.eg/service?article_code=11852

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

El-Sayed Mohamed El-Habibi; Magda Protective Effect of Date Palm Extracts on Cadmium-Induced Infertility in Male Rats

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Article

Created At

22 Jan 2023