12049

Assessment of the Relation between Fetal Hemodynamic Indices in Late Pregnancy and Birth Weight in Gestational Diabetic Mellitus Mothers: A correlational study

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Last updated: 03 Jan 2025

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Abstract

Background: The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed at investigating the correlations between fetal hemodynamics, fetal growth indices in late pregnancy and birth weight in GDM. Methods: A total of 180 women with GDM and 180 normal controls (NC) with singleton gestation and presented between 38-40 weeks gestation were enrolled in this study. Fetal hemodynamic indices, including the systolic/diastolic ratio (S/D), resistance index (RI), pulsatility index (PI) of umbilical artery (UA), middle cerebral artery (MCA), and renal artery (RA), were collected. Fetal growth indices, including biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur length (FL), were also measured by ultrasound. Birth weight, mode of delivery and need for Neonatal ICU admission data were collected. Results: The independent samples t-test showed that BPD, HC, AC and FL were larger in GDM than in NC (P < 0.05). Birth weight was higher in GDM than in NC (P < 0.001).  Among all included women, there was a highly statistically insignificant difference between GDM and NC groups as regard all ultrasound indices including UA_S/D, UA_RI, UA_PI, MCA_S/D, MCA_RI, MCA_PI, RA_S/D, RA_RI and RA_PI (P>0.05). Pearson's correlation analysis showed in GDM group that there was a highly statistically significant negative correlation between birth weight and the following ultrasound indices: (UA_RI, UA_S/D, UA_PI, MCA_RI and MCA_PI) and that there was a statistically significant positive correlation between birth weight & RA_RI (P<0.01)  (r = −0.273, −0.453, −0.537, −0.237, −0.265 and 0.169 respectively, P < 0.05), but As regard NC group there was a highly statistically significant negative correlation between birth weight and the following ultrasound indices: (UA_S/D, UA_RI, UA_PI and MCA_PI) (r = 0.148, -0.360, -0.252 and -0.184 respectively, P < 0.05) but no correlation was found with any of renal artery indices (P > 0.05). Conclusions: Fetal hemodynamic indices in late pregnancy might be helpful for estimating newborn birth weight in women with GDM.

DOI

10.21608/ejhm.2018.12049

Keywords

fetus, Gestational diabetes mellitus, infant, middle cerebral artery, Renal artery, Ultrasound, umbilical artery

Authors

First Name

Magdy

Last Name

Abd el Gawad

MiddleName

Mohamed Mahmoud

Affiliation

Obstetrics and Gynaecology Faculty of Medicine – Ain Shams University.

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Orcid

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First Name

Mohamed

Last Name

Moustafa

MiddleName

Hussain

Affiliation

Obstetrics and Gynaecology Faculty of Medicine – Ain Shams University.

Email

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City

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Orcid

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First Name

Laila

Last Name

Farid

MiddleName

Aly

Affiliation

Obstetrics and Gynaecology Faculty of Medicine – Ain Shams University.

Email

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City

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Orcid

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First Name

Noha

Last Name

Abd El Aziz

MiddleName

Emad El Din

Affiliation

Obstetrics and Gynecology at Manshyet El Bakry General Hospital.

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Volume

73

Article Issue

1

Related Issue

2169

Issue Date

2018-10-01

Receive Date

2018-08-31

Publish Date

2018-10-01

Page Start

5,856

Page End

5,864

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_12049.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=12049

Order

19

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Assessment of the Relation between Fetal Hemodynamic Indices in Late Pregnancy and Birth Weight in Gestational Diabetic Mellitus Mothers: A correlational study

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Article

Created At

22 Jan 2023