Background: in autism spectrum disorder the range of language abilities varies between total muteness to an apparent grammatically complex language. There is a debate on the effect of autism on syntax development if it is normal, delayed or deviant. Aim of the Work: it was to assess the syntactic profile of ASD children.         Patients and Methods: a cross sectional descriptive research design. The subjects of this study comprised a convenient sample of 20 children diagnosed as ASD and other 20 normal children as control group with age range between 3 years 8 months and 11 years 8 months. Modified Arabic preschool language scale (PLS-4) Test and Stanford Binet intelligence scales, fifth edition were done for all children and Child autism rating scale (CARS) was done for children with ASD. Results: syntax in ASD is significantly delayed compared to the syntax of normal subjects. Significant impairments in certain items of syntax as (Making grammatical judgments or repairing grammatical errors, understanding pronouns or expressing them, retelling sentences or stories, answering logically using negation, expressing jobs in speech, using irregular plurals, using dualization, question formulation, using past tense forms and using words that describe physical state) was found. Conclusion: syntax in ASD was found to be affected and is found to be below the total language level of the study subjects and this was confirmed by sustained repeated impairments in certain items of syntax.