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11877

Comparison between Cabergoline and Coasting in Prevention of Ovarian Hyperstimulation Syndrome and their effect on Intracytoplasmic Sperm Injection Outcome

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Last updated: 03 Jan 2025

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Abstract

Aim of the work: ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, serious and potentially fatal complication of ovarian stimulation, affecting1–14% of all IVF/ICSI cycles. This study aimed to compare cabergoline after hCG administration with delayed hCG administration (coasting) in high risk patients to prevent OHSS in ART cycles. Patients and methods: this prospective comparative randomized study included 100 patients at risk of OHSS performed in the Assisted Reproductive Technologies Center, Al-Azhar University and in Private IVF Centers during the period from November, 2015 to October, 2016. Results: comparison between the two groups showed no significant difference regarding age, BMI, presence of risk factors of OHSS, but there was a significant difference regarding FSH, LH  and the mean diameter of follicles on day of hCG administration. Conclusion: PCOS affects 5 to 10% of women of childbearing age and is the most common cause of anovulatory infertility in developed countries. Recommendations: further studies including large number of cases and for longer duration will further confirm the efficacy of cabergoline and coasting on prevention of OHSS.

DOI

10.21608/ejhm.2018.11877

Keywords

Cabergoline, Coasting, ovarian hyperstimulation syndrome, Intracytoplasmic Sperm Injection Outcome

Authors

First Name

Ismaeil M.

Last Name

El-Garhy

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al Azhar University

Email

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City

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Orcid

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First Name

Ahmed O.

Last Name

Abdel Motaal

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al Azhar University

Email

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City

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Orcid

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First Name

Mohamed G.

Last Name

Omr

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Al Azhar University

Email

mohamedgamalomer90@gmail.com

City

-

Orcid

-

Volume

73

Article Issue

1

Related Issue

2169

Issue Date

2018-10-01

Receive Date

2018-08-29

Publish Date

2018-10-01

Page Start

5,753

Page End

5,769

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 73_Issue 1_Pages 5753-5769.pdf

PDF . 503.6kB

Link

https://ejhm.journals.ekb.eg/article_11877.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=11877

Order

7

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparison between Cabergoline and Coasting in Prevention of Ovarian Hyperstimulation Syndrome and their effect on Intracytoplasmic Sperm Injection Outcome

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Article

Created At

22 Jan 2023