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11729

Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome

Article

Last updated: 03 Jan 2025

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Abstract

Background: Gestational diabetes is diabetes, or high blood sugar levels, that develops during pregnancy.  It occurs in about 4% of all pregnancies. It is usually diagnosed in the later stages of pregnancy and often occurs in women who have no prior history of diabetes. Aim of the Work: To assess the predictive value of elevated glycosylated hemoglobin at 34 weeks' gestation with adverse fetal outcome as regard fetal macrosomia and neonatal hypoglycemia. Patients and Methods: This prospective longitudinal cohort study included 98 pregnant women who were recruited from the obstetric outpatient clinic and department at Al-Galaa Teaching Hospital. Results:  HbA1c ≥7.9 has sensitivity of 88.1% and specificity of 66.1%, in prediction of macrosomia and a sensitivity of91.9% and specificity of 63.9% in prediction of Hypoglycemia. Conclusion: HbA1c ≥7.9 has moderate diagnostic characteristics in prediction ofmacrosomia, and hypoglycemia, low diagnostic characteristics in prediction of RDS and NICU. Recommendations: Use of HbA1C is recommended for patients with GDM for screening, follow up and prediction of adverse neonatal outcomes.  

DOI

10.12816/0040617

Keywords

Glycosylated Hemoglobin, gestation, adverse neonatal outcome, Fetal Macrosomia

Authors

First Name

Hassan T.

Last Name

Khairy

MiddleName

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Affiliation

Department of Gynecology, Faculty of Medicine, Ain Shams University

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Orcid

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First Name

Mohamed E.

Last Name

Mohamed

MiddleName

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Affiliation

Department of Gynecology, Faculty of Medicine, Ain Shams University

Email

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City

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Orcid

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First Name

Sherif H.

Last Name

Hussain

MiddleName

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Affiliation

Department of Gynecology, Faculty of Medicine, Ain Shams University

Email

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City

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Orcid

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First Name

Mohamed S.

Last Name

Al-Refaie

MiddleName

-

Affiliation

Department of Gynecology, Faculty of Medicine, Ain Shams University

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Orcid

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Volume

69

Article Issue

2

Related Issue

2165

Issue Date

2017-10-01

Receive Date

2018-08-28

Publish Date

2017-10-01

Page Start

1,880

Page End

1,888

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_11729.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=11729

Order

16

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome

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Article

Created At

22 Jan 2023