Background: Renal inflammatory diseases range from mild to severe, acute to chronic and may be associated with predisposing risk factors like diabetes mellitus, human immunodeficiency virus (HIV), leukemia, vesicoureteric reflux and staghorn calculi. Ultrasound (US) is the initial screening modality and is used for guiding interventions as well. The role of intravenous urography (IVU) has diminished lately, however it still remains the best modality to diagnose calyceal irregularity of early tuberculosis, papillary necrosis and to evaluate congenital anomalies. Aim of Work: The study aim to highlight the value of multidetecter C.T imaging in assessment of renal inflammatory diseases. Conclusion: C.T has the ability to diagnose and assess renal infection site and extension of infection to pararenal fascia, renal infection unilateral or bilateral and infection focal or diffused. CT has important role in assessment of complication and follow up of patients. CT guided FNAB can be done to diagnose renal infection and differentiate between infection.