Purpose: To report the outcomes and complications of iris-fixated posterior chamber intraocular lenses (PCIOL) using Siepser sliding knot technique in suturing one or both haptics. Methods: Retrospective, observational case study involving surgical placement of a foldable iris-sutured PCIOL using the Siepser sliding knot technique. This study was carried out between September 2008 and March 2010 and reviewed by seven anterior segment surgeons. Outcome measures included change in visual acuity (VA) and complications. Results: 30 eyes of 29 patients were included. 26 PCIOLs (86.7%) had the Siepser sliding knot technique fixed on both haptics whereas 4 (13.3%) had the PCIOL knot was fixed over a single haptics. Mean age of patients at the time of surgery was 50.5 years ± 24.5 (Range, 7 to 79 years). Preoperatively, the mean Snellen decimal uncorrected VA (UCVA) was 0.158 ± 0.163 and the mean preoperative best-corrected VA (BCVA) was 0.249 ± 0.195. Postoperatively, the mean Snellen decimal BCVA was 0.383 ± 0.232. 22 patients (73.3%) showed  improved  BCVA following surgery. The mean follow up period was 6.9 months ± 5.5 (Range, 1 to 16 months). Complications included elevated intraocular pressure (IOP) (10%, n=3), transient diplopia (6.7%, n=2), decompensated cornea (3.3%, n=1), wound leak (3.3%, n=1) and dislocated PCIOL (3.3%, n=1). Conclusion: Iris-fixated PCIOL using Siepser sliding knot technique in suturing one or both haptics is a useful and safe technique for PCIOL implantation in the event of a partial or complete absence of capsular support.