Background: many reasons can lead to an aphakia without sufficient capsular support for a posterior chamber intraocular lens, such as intraoperative complications during phacoemulsification, intracapsular cataract extraction, ocular trauma and lens dislocation caused by various reasons. Aim of the Work: was to compare retropupillary fixation of an iris-claw IOL (artisan aphakia lens) with transscleral suturing fixation of aposterior chamber IOL for aphakic eyes without sufficient capsular support as regards safety, visual recovery and complications of the procedure. Material and Methods: this a prospective interventional case series study included a total of 45 eyes of 42 patients of the age group 13-60 years, selected from those attending the Ophthalmology Department at Al-Azhar University Hospitals according to the inclusion and exclusion criteria. Results: in group A, the duration ranged from 15 to 45 min with a mean of 30.30±6.06min, in group B, the duration ranged from 35 to 85 min with a mean 60.60±12.41min. The P-Value was< 0. 001. The IOP showed at day 1 postoperative was higher in group B 20.06±4 than group A A16.40±3.9 p value was 0.012, however IOP was nearly at the same level at the end of the follow up period 15.23±3.63 in group A and 15.23±3.63 in group B with p value 0.713. Conclusion: the results of our study indicated that IC-IOL and SF-PCIOL implantations are both satisfactory in correcting aphakia without sufficient capsular support to hold an IOL in the posterior capsule.