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Rheumatoid Arthritis, Pathophysiology and Management

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Last updated: 24 Dec 2024

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Abstract

Introduction: Rheumatoid arthritis is considered one of the most common, and particularly attacks the joint causing significant individual and community burden, and present with articular as well as extra articular manifestation. Treatment modalities of rheumatoid arthritis have dramatically improved in recent years, significantly decreasing long-term auricular and extra-auricular complications. Aim of the work: this review was aimedto study the pathophysiology, clinical picture, and management of rheumatoid arthritis, with focus on the newer modalities.  
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: rheumatoid arthritis, chronic inflammatory disorders, genetic of rheumatoid arthritis, management of rheumatoid arthritis, DMARD, biological agents
Conclusion: The newer modality of treatment must include disease-modifying antirheumatic drug (DMARDs) which must be started as early as possible. Combining DMARDs with corticosteroids will result in significantly better outcomes than monotherapy with any DMARD and decrease long term morbidity associated with this condition.

Keywords

chronic inflammatory disorders, management of rheumatoid arthritis, DMARD, Biological agents, Rheumatoid Arthritis

Authors

First Name

Ghofran Noor Mohammad

Last Name

Qorban

MiddleName

-

Affiliation

King Abdulaziz University Hospital

Email

-

City

-

Orcid

-

First Name

Mohannad Mobarak Omar

Last Name

Badghaish

MiddleName

-

Affiliation

King Abdulaziz University

Email

dr.mbadghaish@gmail.com

City

-

Orcid

-

First Name

Abdulmohsen Shawan

Last Name

Albaqami

MiddleName

-

Affiliation

Imam Muhammad Ibn Saud Islamic University

Email

-

City

-

Orcid

-

First Name

Ameera Ahmad

Last Name

Nemer

MiddleName

-

Affiliation

Immam Abdulrahman Faisal University

Email

-

City

-

Orcid

-

First Name

Aisha Jamal

Last Name

Alali

MiddleName

-

Affiliation

Arabian Gulf University

Email

-

City

-

Orcid

-

First Name

Rawan Fouad Hassan

Last Name

Al Yaqoub

MiddleName

-

Affiliation

Ibn Sina National College

Email

-

City

-

Orcid

-

First Name

Homoud Abdulaziz

Last Name

Alshamrani

MiddleName

-

Affiliation

Primary Health Care Center – Riyadh

Email

-

City

-

Orcid

-

First Name

Omar Hasan

Last Name

Badahman

MiddleName

-

Affiliation

King Abdulaziz University

Email

-

City

-

Orcid

-

First Name

Rahma Abdulkarim

Last Name

Ansaif

MiddleName

-

Affiliation

Alexandria University

Email

-

City

-

Orcid

-

First Name

Metab Ali

Last Name

Alasmari

MiddleName

-

Affiliation

Gizan Militarily Hospital

Email

-

City

-

Orcid

-

First Name

Arwa Yahya

Last Name

Alghamdi

MiddleName

-

Affiliation

Immam Abdulrahman Faisal University

Email

-

City

-

Orcid

-

First Name

Hussain Ahmad Saud

Last Name

Alshareef

MiddleName

-

Affiliation

King Fahad Hospital, Madinah

Email

-

City

-

Orcid

-

First Name

Alanoud Mohammed

Last Name

Aljadeed

MiddleName

-

Affiliation

Ibn Sina National College

Email

-

City

-

Orcid

-

First Name

Ayman Ahmed

Last Name

Almohammed

MiddleName

-

Affiliation

King Faisal University

Email

-

City

-

Orcid

-

First Name

Doaa Mohammad

Last Name

Filmban

MiddleName

-

Affiliation

Al Noor Specialist Hospital

Email

-

City

-

Orcid

-

First Name

Abdulrahman Saleh

Last Name

Alaql

MiddleName

-

Affiliation

Al Adeel Primary Health Care Center

Email

-

City

-

Orcid

-

Volume

70

Article Issue

11

Related Issue

1821

Issue Date

2018-01-01

Receive Date

2018-07-21

Publish Date

2018-01-01

Page Start

1,898

Page End

1,903

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 70_Issue 11_Pages 1898-1903.pdf

PDF . 248.2kB

Link

https://ejhm.journals.ekb.eg/article_9388.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=9388

Order

5

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Rheumatoid Arthritis, Pathophysiology and Management

Details

Type

Article

Created At

22 Jan 2023