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Assessment of Corneal Higher Order Aberrations Before and After Corneal Collagen Cross-Linking in Patients with Keratoconus

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Last updated: 03 Jan 2025

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Abstract

Purpose: This study aimed at assessing the shortterm effect of corneal collagen crosslinking on higher order aberrations of cornea in patients with keratoconus using corneal topography.
Patients and Methods: The study was a prospective cohort study that was conducted in a private specialized eye hospital on 40 eyes of 28 keratoconus patients. Each patient was fully assessed preoperatively including doing corneal topography using Pentacam® HR. Transepithelial accelerated CXL was done to all patients. Postoperative corneal topography was done at six months and data was retrieved and analyzed.
Results: RMS HOA recorded a higher mean value preoperatively, with a high statistically significant difference (p=0.00). All elements of HOAs showed lower postoperative values except for trefoil 30o. The difference was statistically significant in comma 0o, comma 90o, spherical aberrations and fifth order comma 90° (p=0.026, p= 0.003, p=0.005, and p=0.001 respectively).
Conclusion: Transepithelial corneal collagen cross-linking improves corneal higher order aberrations. The maximum effect of the procedure is on comma 0o, comma 90o, spherical aberrations and fifth order comma 90° elements.

DOI

10.21608/ejhm.2018.9123

Keywords

Keratoconus, Corneal Collagen cross-linking, Higher order aberrations

Authors

First Name

Mo'mena

Last Name

A.A.,

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

m.abd_elrazeik@yahoo.com

City

-

Orcid

-

First Name

Moamen

Last Name

S.

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

A.

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

Tamer

Last Name

E.M.

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

Rafeek

Last Name

E.G.

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

72

Article Issue

3

Related Issue

1778

Issue Date

2018-07-01

Receive Date

2018-07-15

Publish Date

2018-07-01

Page Start

4,100

Page End

4,103

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 72_Issue 3_Pages 4100-4103.pdf

PDF . 288.8kB

Link

https://ejhm.journals.ekb.eg/article_9123.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=9123

Order

11

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Assessment of Corneal Higher Order Aberrations Before and After Corneal Collagen Cross-Linking in Patients with Keratoconus

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Article

Created At

22 Jan 2023