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The Use of Levonorgestrel-Releasing System (Metraplant-E) in the Treatment of Abnormal Uterine Bleeding

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Last updated: 24 Dec 2024

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Abstract

Background: Dysfunctional uterine bleeding (DUB) is one of the commonest condition for which patient seeks out medical consultation. The prevalence increases with the increase of age peaking before menopause. Objective: The aim of this work is to evaluate the effect of this new form of levonorgestrel-releasing IUD on the treatment of patients with abnormal uterine bleeding.
Subjects and methods: A prospective age-specific comparative analysis of 61 peri-menopausal women presented with dysfunctional uterine bleeding who constituted the study group. They underwent hysteroscopy and endometrial sampling during an 18 months period from June 2014 to January 2016 at Ain Shams University Materity Hospital. Prior to metraplant-E application, all the patients in this study were in the age of 25-58 years old.
Results: The role of Metraplant-E in the treatment of abnormal uterine bleeding (AUB) was evaluated. Sixty-one women with failed attempt(s) of medical treatment unwilling or unfit for hysterectomy were treated with Metaplant- E. Menstrual blood loss was assessed by pictoral bleeding assessment chart (PBAC), bleeding index (B.I) and total bleeding score (T.B.S/month). The bleeding patterns in the form of the mean menstrual blood loss estimated by bleeding index and the mean menstrual loss estimated by the total bleeding score/month and PBAC decreased significantly (p = 0.001). The quality of life scale (Likert scale) improved significantly (p = 0.001). All 15 cases who had endometrial sampling demonstrated progestational effect on histo-pathological examination.
Conclusion: Metraplant-E was found to be effective in managing dysfunctional menorrhagia on both clinical and histopathological levels.

DOI

10.21608/ejhm.2018.9082

Keywords

Metraplant-E, LNG-IUS, menorrhagia, contraceptives

Authors

First Name

Mohamed Ezz-Eldin A. Azzam*, Magd Eldin M. Mohamed, Laila A. Farid, Alshaimaa AA Mahmoud,

Last Name

Reem Abdelazeem Hussein, Alaa Rashid

MiddleName

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Affiliation

Department of Obstetrics and Gynecology and Early Cancer Detection Unit, Ain Shams University, Cairo, Egypt.

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City

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Orcid

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Volume

72

Article Issue

2

Related Issue

1774

Issue Date

2018-07-01

Receive Date

2018-04-12

Publish Date

2018-07-01

Page Start

3,979

Page End

3,985

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 72_Issue 2_Pages 3979-3985.pdf

PDF . 601.4kB

Link

https://ejhm.journals.ekb.eg/article_9082.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=9082

Order

19

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

The Use of Levonorgestrel-Releasing System (Metraplant-E) in the Treatment of Abnormal Uterine Bleeding

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Article

Created At

22 Jan 2023