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9076

Evaluation of the Most Common Complications of Sickle Cell Anemia and Management in Children: Simple Literature Review

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Last updated: 03 Jan 2025

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Abstract

Background: Sickle cell anemia is an autosomal structural defect that affect the hemoglobin. It is associated with reduction in the RBC life span especially under stress. As a result of this structural defect the RBCs takes a sickle shape which is associated with a lot of complications that significantly have an effect on the patient's life. Objective: In this study, we aim at evaluating the most common complication of sickle cell anemia. Also, the assessment of the various management plans to prevent it if occurred. Methods: PubMed database were used for articles selection as well as all relevant articles to our research interest with the following topics: Sickle cell anemia, Complications, Mortality, Prevention and Management. We excluded other articles, which are not related to this field. The data were extracted according to specific form in which it is going to be reviewed by the group members. Conclusion: Sickle cell anemia have various complications that have impact on quality of life and arise from effect of three main pathophysiological mechanisms i.e. Vasooclussive, hyper-haemolytic and infective complications. Hydroxyurea, chronic blood transfusion, and routine Transcranial Doppler Ultrasound are still the most useful preventive measures of SCA complications.

DOI

10.21608/ejhm.2018.9076

Keywords

Sickle cell anemia, Complications, quality of life, children

Authors

First Name

Ghadeer Awad Alenazy1, Asma Mutni Almutairi2, Lamia Aiad Al-Onazi2, Ghaid Mohammed H Alkharaz3,

Last Name

Shuruq Hassan Alsulami4, Manal Nasser Alotaibi4, Eyman Abdulmajeed Alfaraj5,

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Affiliation

1- Hail University, 2- Qassim University, 3- Unaizah College of Medicine, 4- Ibn Sina Medical College, 5- Imam Abdulrahman University,

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First Name

Afnan Hussain Alshaikhali5, Mahabbat Nadin Anam A6,

Last Name

Ammar Mohammad M Bahati7

MiddleName

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Affiliation

6- King Saud bin Abdulaziz University for Health Sciences, 7- Umm Al-Qura University

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Volume

72

Article Issue

2

Related Issue

1774

Issue Date

2018-07-01

Receive Date

2018-04-21

Publish Date

2018-07-01

Page Start

3,951

Page End

3,960

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 72_Issue 2_Pages 3951-3960.pdf

PDF . 384.6kB

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https://ejhm.journals.ekb.eg/article_9076.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=9076

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16

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Evaluation of the Most Common Complications of Sickle Cell Anemia and Management in Children: Simple Literature Review

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Article

Created At

22 Jan 2023