Background: Thyroid diseases are one of the most prevalent endocrinopathies globally (1). Most of the thyroid diseases treated surgically. The operation duration is under multiple factors can be predicted preoperatively (2). Hypocalcaemia and nerve injury are serious complication after thyroid surgery and we hypothesized it could be prevented by simple measures to avoid such complications.
Objective: Was to assess the correlation between thyroidectomy operating time, histo-pathological diagnosis of thyroid disease and pre-operative vitamin D supplementation with post thyroidectomy complications mainly hypocalcaemia and nerve injury. Method: An observational retrospective cohort study with a total of 187 patients who underwent thyroidectomy from October 7th 2013 to January 4th 2018 were included in this study. Data were analyzed for demographic information including age, sex, nationality, height and weight. Information about the use of vitamin D supplementation before or after the operation, the clinical and the histological diagnosis of thyroid diseases, the name of the procedure (partial or total thyroidectomy), and the presence of any complications. Result: The mean age of the patients was 39.7±12.71 years. 81.8%(153) were females and 18.2%(34) were males. 53.5%(100) were given Vitamin-D supplements before or after the surgery. Histopathology showed that the most prevalent type was papillary Carcinoma accounting for 68 (36.4%). No significant association between histological diagnosis and complication of hypocalcaemia and nerve injury. Mean duration of surgery performed was 135.61±47.668. 83 of our patients suffered from hypocalcaemia and 6 suffered from nerve injury. When correlating between duration of surgery with hypocalcaemia and nerve injury, The independent t-test was associated with statistically insignificant effect t(182)= -1.85 , p= 0.066 (>0.05) for hypocalcaemia and t(185)= -0.075 , p= 0.940 (>0.05) for nerve injury.
Conclusion: Our study suggested that there was no significant correlation between the duration of surgery as well as histo-pathological diagnosis and the development of post-operative hypocalcaemia and nerve injury.