Background: the dyslipidemia and its associated risk factors and co-morbid diseases are the focus of many studies in KSA, however the data regarding the prevalence are very little. Objectives: this study aimed to assess the risk factors of dyslipidemia and its association with the subject's demographics and life style pattern in Kingdom of Saudi Arabia (KSA). Methods: this was a cross-sectional study based on a check list and questionnaire sheet conducted for 6 months among 840 Saudi adults. Results: about 33%of the subjects were suffered from dyslipidemia after checking their lipid profile and anthropometric measures. The subjects were divided into two groups: group I included dyslipidemic subjects and group II included control subjects.  The older age and jobless subjects showed a significant association with the prevalence of dyslipidemia. Group I showed a significant association between dyslipidemia and comorbid conditions than group II. The irregular physical activity, consuming less healthy food and consuming more fast food are significantly related to Group I than group II. Conclusion: dyslipidemia is common among Saudi subjects and associated with health problem as hypertension, diabetes and obesity as well as bad lifestyle habits.