Background: Severe complications and morbidities are associated with diabetes, especially with poor control of the disease. Diabetes is thought to be the most common cause of renal failure and responsible for about half cases of end stage kidney disease, coronary artery disease, myocardial infarctions, congestive heart failure, strokes, foot problems and eye damage. The presence of any chronic illness with diabetes causes deterioration clinical status which makes tight glycemic control a necessity to improve quality of life and prevent these serious and potentially fatal complications. Aim: This review was aimed to shine light upon measures that must be taken to improve the quality of life in a patient with diabetes mellitus. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1997, through February 2017. The following search terms were used: diabetes mellitus, chronic disorders, management of chronic diabetes, quality of life in diabetic patients, weight control, diabetic diet Conclusion: Many factors affect the quality of life in diabetic patients including glycemic control, prevention of complications, and socioeconomic/demographic factors. Lifestyle modifications like weight loss and good dietary habits can help patients manage their disease better. Insulin pumps have eased the management of this disease and improved patients' quality of life drastically. Patients should be educated about the importance of support groups that may lead to a better quality of life.