Background: Liver cirrhosis is chronic disease associated with high mortality and morbidity rates all over the world. Objectives: evaluating the knowledge of adult Saudi population toward liver cirrhosis.        Methods: A qualitative study was conducted in Kingdom of Saudi Arabia among 820 Saudi subjects during the period from October to December 2017. Results: A total of 820 subjects were enrolled in the study. All the subjects had good knowledge regarding the definition of liver cirrhosis. The majority of subjects had moderate knowledge regarding the causes, prognosis and treatment of liver cirrhosis. More than half of the subjects (54%) had good knowledge regarding liver cirrhosis while 46% had poor knowledge. There was a positive significant association between younger age and high-level education with good awareness about cirrhosis of liver Conclusion: The level of awareness among Saudi population toward LC was moderate which necessitates encouraging the educational campaigns on T.V, internet and all over the whole parts of KSA.